Distribution of Helicobacter pylori infection and abnormal body- mass index (BMI) in a developing country
Introduction: Helicobacter pylori is prevalent in developing nations. We determined the prevalence of H. pylori infection in relation to body-mass index (BMI) of dyspeptic patients and related comorbid conditions. Methodology: In a cross-sectional study, dyspeptic patients were enrolled and test...
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The Journal of Infection in Developing Countries
2018-05-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/10051 |
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| author | Basit Siddiqui Javed Yakoob Zaigham Abbas Rabeea Azmat Syeda Sadia Fatima Safia Awan |
| author_facet | Basit Siddiqui Javed Yakoob Zaigham Abbas Rabeea Azmat Syeda Sadia Fatima Safia Awan |
| author_sort | Basit Siddiqui |
| collection | DOAJ |
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Introduction: Helicobacter pylori is prevalent in developing nations. We determined the prevalence of H. pylori infection in relation to body-mass index (BMI) of dyspeptic patients and related comorbid conditions.
Methodology: In a cross-sectional study, dyspeptic patients were enrolled and tested for H. pylori infection. “Underweight” was defined as BMI lower than 18.4; “Healthy” 18.5 to 23; “Overweight” 23.1-27.9; and “Obese” greater than 28.
Results: Six hundred and ninety-eight patients were included, with a mean age of 44 ± 16 years. Males were 373/698, 53%. H. pylori was positive in 399/698, 57%. Underweight were 36 (5%); BMI-healthy 168 (24%); overweight 236 (34%) and obese 258 (37%). H. pylori infection was present in 65/273 BMI-healthy patients ; 24% compared to obese 208/273; 76% (P < 0.001). In the H. pylori- positive with a “healthy” BMI, dyslipidemia was seen in 6/65; 8% compared to obese 53/208; 25% (P = 0.005); type 2 diabetes in 8/65; 12% with a “healthy” BMI compared to obese 54/208; 26% (P = 0.022) and coronary artery disease in 4/65; 6% of BMI-healthy compared to obese 38/208; 18% patients (P = 0.018). Multivariate analysis showed that age 31-50 years (OR 1.77, 95% CI 1.13-2.77), BMI > 23.1 (OR 2.91, 95% CI infection. 2.01-4.20), and type 2 diabetes (OR 2.41, 95% CI 1.43-4.06) were risk factors for H. pylori
Conclusions: H. pylori infection was prevalent in the 31-50-year age group. Abnormal BMI was associated with H. pylori infection.
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| format | Article |
| id | doaj-art-6767a98eaef345cd92246ae9b78d8807 |
| institution | Kabale University |
| issn | 1972-2680 |
| language | English |
| publishDate | 2018-05-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-6767a98eaef345cd92246ae9b78d88072025-08-20T03:52:41ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802018-05-01120510.3855/jidc.10051Distribution of Helicobacter pylori infection and abnormal body- mass index (BMI) in a developing countryBasit Siddiqui0Javed Yakoob1Zaigham Abbas2Rabeea Azmat3Syeda Sadia Fatima4Safia Awan5Aga Khan University Hospital, Karachi, PakistanAga Khan University Hospital, Karachi, PakistanAga Khan University Hospital, Karachi, PakistanAga Khan University Hospital, Karachi, PakistanAga Khan University Hospital, Karachi, PakistanAga Khan University Hospital, Karachi, Pakistan Introduction: Helicobacter pylori is prevalent in developing nations. We determined the prevalence of H. pylori infection in relation to body-mass index (BMI) of dyspeptic patients and related comorbid conditions. Methodology: In a cross-sectional study, dyspeptic patients were enrolled and tested for H. pylori infection. “Underweight” was defined as BMI lower than 18.4; “Healthy” 18.5 to 23; “Overweight” 23.1-27.9; and “Obese” greater than 28. Results: Six hundred and ninety-eight patients were included, with a mean age of 44 ± 16 years. Males were 373/698, 53%. H. pylori was positive in 399/698, 57%. Underweight were 36 (5%); BMI-healthy 168 (24%); overweight 236 (34%) and obese 258 (37%). H. pylori infection was present in 65/273 BMI-healthy patients ; 24% compared to obese 208/273; 76% (P < 0.001). In the H. pylori- positive with a “healthy” BMI, dyslipidemia was seen in 6/65; 8% compared to obese 53/208; 25% (P = 0.005); type 2 diabetes in 8/65; 12% with a “healthy” BMI compared to obese 54/208; 26% (P = 0.022) and coronary artery disease in 4/65; 6% of BMI-healthy compared to obese 38/208; 18% patients (P = 0.018). Multivariate analysis showed that age 31-50 years (OR 1.77, 95% CI 1.13-2.77), BMI > 23.1 (OR 2.91, 95% CI infection. 2.01-4.20), and type 2 diabetes (OR 2.41, 95% CI 1.43-4.06) were risk factors for H. pylori Conclusions: H. pylori infection was prevalent in the 31-50-year age group. Abnormal BMI was associated with H. pylori infection. https://jidc.org/index.php/journal/article/view/10051Helicobacter pyloriBMIoverweighttype 2 diabetes |
| spellingShingle | Basit Siddiqui Javed Yakoob Zaigham Abbas Rabeea Azmat Syeda Sadia Fatima Safia Awan Distribution of Helicobacter pylori infection and abnormal body- mass index (BMI) in a developing country Journal of Infection in Developing Countries Helicobacter pylori BMI overweight type 2 diabetes |
| title | Distribution of Helicobacter pylori infection and abnormal body- mass index (BMI) in a developing country |
| title_full | Distribution of Helicobacter pylori infection and abnormal body- mass index (BMI) in a developing country |
| title_fullStr | Distribution of Helicobacter pylori infection and abnormal body- mass index (BMI) in a developing country |
| title_full_unstemmed | Distribution of Helicobacter pylori infection and abnormal body- mass index (BMI) in a developing country |
| title_short | Distribution of Helicobacter pylori infection and abnormal body- mass index (BMI) in a developing country |
| title_sort | distribution of helicobacter pylori infection and abnormal body mass index bmi in a developing country |
| topic | Helicobacter pylori BMI overweight type 2 diabetes |
| url | https://jidc.org/index.php/journal/article/view/10051 |
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