Crucial roles of Grr1 in splicing and translation of HAC1 mRNA upon unfolded stress response
Abstract In the process of the unfolded protein response (UPR), the Hac1p protein is induced through a complex regulation of the HAC1 mRNA. This includes the mRNA localization on the endoplasmic reticulum (ER) membrane and stress-triggered splicing. In yeast, a specific ribosome ubiquitination proce...
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| Main Authors: | Nichika Sato, Yu Nakano, Yasuko Matsuki, Shota Tomomatsu, Sihan Li, Yoshitaka Matsuo, Toshifumi Inada |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Portfolio
2025-03-01
|
| Series: | Nature Communications |
| Online Access: | https://doi.org/10.1038/s41467-025-57360-1 |
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