The clinical and laboratory manifestations of Iranian patients with cystic fibrosis
Cystic fibrosis (CF) is a hereditary disease, characterized by chronic pulmonary disease, pancreatic insufficiency and abnormal electrolytes in the sweat. In order to evaluate the clinical manifestations and laboratory findings of Iranian children with CF during a 10-year period, 243 CF patie...
Saved in:
| Main Authors: | , , , , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hacettepe University Institute of Child Health
2010-04-01
|
| Series: | The Turkish Journal of Pediatrics |
| Online Access: | https://turkjpediatr.org/article/view/4979 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1850042862589181952 |
|---|---|
| author | Gholamhossein Fallahi Mehri Najafi Fatemeh Farhmand Fatemeh Bazvand Maedeh Ahmadi Faezeh Ahmadi Kambiz Eftekhari Ahmad Khodad Farzaneh Motamed Gholamreza Khatami Asghar Aghamohammadi Nima Rezaei |
| author_facet | Gholamhossein Fallahi Mehri Najafi Fatemeh Farhmand Fatemeh Bazvand Maedeh Ahmadi Faezeh Ahmadi Kambiz Eftekhari Ahmad Khodad Farzaneh Motamed Gholamreza Khatami Asghar Aghamohammadi Nima Rezaei |
| author_sort | Gholamhossein Fallahi |
| collection | DOAJ |
| description |
Cystic fibrosis (CF) is a hereditary disease, characterized by chronic pulmonary disease, pancreatic insufficiency and abnormal electrolytes in the sweat. In order to evaluate the clinical manifestations and laboratory findings of Iranian children with CF during a 10-year period, 243 CF patients, with a median age of 5 months, were investigated in this study. The most common manifestations were gastrointestinal disorders and respiratory manifestations. Cough was the most common symptom, followed by malnutrition, diarrhea, respiratory distress, and vomiting. The frequency of these findings after treatment was significantly decreased in comparison with the period before diagnosis. During the mean follow-up of 40.9 months, seven cases died due to severe infections. Cystic fibrosis as a common genetic disorder should be considered in any child with recurrent gastrointestinal and respiratory manifestations, since delayed diagnosis could lead to severe complications and even death in this group of patients.
|
| format | Article |
| id | doaj-art-675df5f9b7a645ec9afbb4236cea65eb |
| institution | DOAJ |
| issn | 0041-4301 2791-6421 |
| language | English |
| publishDate | 2010-04-01 |
| publisher | Hacettepe University Institute of Child Health |
| record_format | Article |
| series | The Turkish Journal of Pediatrics |
| spelling | doaj-art-675df5f9b7a645ec9afbb4236cea65eb2025-08-20T02:55:24ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212010-04-01522The clinical and laboratory manifestations of Iranian patients with cystic fibrosisGholamhossein Fallahi0Mehri NajafiFatemeh FarhmandFatemeh BazvandMaedeh AhmadiFaezeh AhmadiKambiz EftekhariAhmad KhodadFarzaneh MotamedGholamreza KhatamiAsghar AghamohammadiNima RezaeiDepartment of Pediatrics, Pediatrics Center of Excellence, Children's Medical Center, Tehran, Iran. Cystic fibrosis (CF) is a hereditary disease, characterized by chronic pulmonary disease, pancreatic insufficiency and abnormal electrolytes in the sweat. In order to evaluate the clinical manifestations and laboratory findings of Iranian children with CF during a 10-year period, 243 CF patients, with a median age of 5 months, were investigated in this study. The most common manifestations were gastrointestinal disorders and respiratory manifestations. Cough was the most common symptom, followed by malnutrition, diarrhea, respiratory distress, and vomiting. The frequency of these findings after treatment was significantly decreased in comparison with the period before diagnosis. During the mean follow-up of 40.9 months, seven cases died due to severe infections. Cystic fibrosis as a common genetic disorder should be considered in any child with recurrent gastrointestinal and respiratory manifestations, since delayed diagnosis could lead to severe complications and even death in this group of patients. https://turkjpediatr.org/article/view/4979 |
| spellingShingle | Gholamhossein Fallahi Mehri Najafi Fatemeh Farhmand Fatemeh Bazvand Maedeh Ahmadi Faezeh Ahmadi Kambiz Eftekhari Ahmad Khodad Farzaneh Motamed Gholamreza Khatami Asghar Aghamohammadi Nima Rezaei The clinical and laboratory manifestations of Iranian patients with cystic fibrosis The Turkish Journal of Pediatrics |
| title | The clinical and laboratory manifestations of Iranian patients with cystic fibrosis |
| title_full | The clinical and laboratory manifestations of Iranian patients with cystic fibrosis |
| title_fullStr | The clinical and laboratory manifestations of Iranian patients with cystic fibrosis |
| title_full_unstemmed | The clinical and laboratory manifestations of Iranian patients with cystic fibrosis |
| title_short | The clinical and laboratory manifestations of Iranian patients with cystic fibrosis |
| title_sort | clinical and laboratory manifestations of iranian patients with cystic fibrosis |
| url | https://turkjpediatr.org/article/view/4979 |
| work_keys_str_mv | AT gholamhosseinfallahi theclinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT mehrinajafi theclinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT fatemehfarhmand theclinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT fatemehbazvand theclinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT maedehahmadi theclinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT faezehahmadi theclinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT kambizeftekhari theclinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT ahmadkhodad theclinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT farzanehmotamed theclinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT gholamrezakhatami theclinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT asgharaghamohammadi theclinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT nimarezaei theclinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT gholamhosseinfallahi clinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT mehrinajafi clinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT fatemehfarhmand clinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT fatemehbazvand clinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT maedehahmadi clinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT faezehahmadi clinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT kambizeftekhari clinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT ahmadkhodad clinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT farzanehmotamed clinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT gholamrezakhatami clinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT asgharaghamohammadi clinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis AT nimarezaei clinicalandlaboratorymanifestationsofiranianpatientswithcysticfibrosis |