Endoscopic Endonasal Approach to Orbital Malignant Peripheral Nerve Sheath Tumor: A Minimally Invasive Method for Rare Orbital Tumor—Case Report and Review of Literature

Malignant peripheral nerve sheath tumors (MPNSTs) are uncommon tumors that rarely occur in the orbit. Malignant orbital tumors are always a challenge to remove completely. We present the case of a 42-year man with painful movement of the left eye and restriction of adduction of the left eye causing...

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Main Authors: Praveen M. Ganigi, Arijit Chakraborty, K.M. Bopanna, Sathwik R. Shetty
Format: Article
Language:English
Published: Thieme Medical and Scientific Publishers Pvt. Ltd. 2025-03-01
Series:Indian Journal of Neurosurgery
Subjects:
Online Access:http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1775973
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author Praveen M. Ganigi
Arijit Chakraborty
K.M. Bopanna
Sathwik R. Shetty
author_facet Praveen M. Ganigi
Arijit Chakraborty
K.M. Bopanna
Sathwik R. Shetty
author_sort Praveen M. Ganigi
collection DOAJ
description Malignant peripheral nerve sheath tumors (MPNSTs) are uncommon tumors that rarely occur in the orbit. Malignant orbital tumors are always a challenge to remove completely. We present the case of a 42-year man with painful movement of the left eye and restriction of adduction of the left eye causing double vision. Magnetic resonance imaging (MRI) of the brain/orbit revealed intraconal tumor located inferomedial to the optic nerve. The imaging features were suggestive of schwannoma or cavernoma. Gross total resection of the tumor was done with an endoscopic endonasal intraconal approach. The histopathology revealed an MPNST. The patient received adjuvant radiotherapy and chemotherapy. His left eye adduction recovered completely and he had no local recurrence or systemic metastasis on follow-up evaluation.
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issn 2277-954X
2277-9167
language English
publishDate 2025-03-01
publisher Thieme Medical and Scientific Publishers Pvt. Ltd.
record_format Article
series Indian Journal of Neurosurgery
spelling doaj-art-6751a399ee6348fca8301a47c16c50722025-08-20T01:57:34ZengThieme Medical and Scientific Publishers Pvt. Ltd.Indian Journal of Neurosurgery2277-954X2277-91672025-03-01140107607910.1055/s-0043-1775973Endoscopic Endonasal Approach to Orbital Malignant Peripheral Nerve Sheath Tumor: A Minimally Invasive Method for Rare Orbital Tumor—Case Report and Review of LiteraturePraveen M. Ganigi0Arijit Chakraborty1https://orcid.org/0000-0003-1664-8998K.M. Bopanna2Sathwik R. Shetty3Manipal Hospital Bangalore, Bengaluru, Karnataka, IndiaManipal Hospital Bangalore, Bengaluru, Karnataka, IndiaDepartment of Neurosurgery, Manipal Hospital Bangalore, Bengaluru, Karnataka, IndiaManipal Hospital Bangalore, Bengaluru, Karnataka, IndiaMalignant peripheral nerve sheath tumors (MPNSTs) are uncommon tumors that rarely occur in the orbit. Malignant orbital tumors are always a challenge to remove completely. We present the case of a 42-year man with painful movement of the left eye and restriction of adduction of the left eye causing double vision. Magnetic resonance imaging (MRI) of the brain/orbit revealed intraconal tumor located inferomedial to the optic nerve. The imaging features were suggestive of schwannoma or cavernoma. Gross total resection of the tumor was done with an endoscopic endonasal intraconal approach. The histopathology revealed an MPNST. The patient received adjuvant radiotherapy and chemotherapy. His left eye adduction recovered completely and he had no local recurrence or systemic metastasis on follow-up evaluation.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1775973MPNSTextremely raremalignantintraconalendoscopic transnasalgross total
spellingShingle Praveen M. Ganigi
Arijit Chakraborty
K.M. Bopanna
Sathwik R. Shetty
Endoscopic Endonasal Approach to Orbital Malignant Peripheral Nerve Sheath Tumor: A Minimally Invasive Method for Rare Orbital Tumor—Case Report and Review of Literature
Indian Journal of Neurosurgery
MPNST
extremely rare
malignant
intraconal
endoscopic transnasal
gross total
title Endoscopic Endonasal Approach to Orbital Malignant Peripheral Nerve Sheath Tumor: A Minimally Invasive Method for Rare Orbital Tumor—Case Report and Review of Literature
title_full Endoscopic Endonasal Approach to Orbital Malignant Peripheral Nerve Sheath Tumor: A Minimally Invasive Method for Rare Orbital Tumor—Case Report and Review of Literature
title_fullStr Endoscopic Endonasal Approach to Orbital Malignant Peripheral Nerve Sheath Tumor: A Minimally Invasive Method for Rare Orbital Tumor—Case Report and Review of Literature
title_full_unstemmed Endoscopic Endonasal Approach to Orbital Malignant Peripheral Nerve Sheath Tumor: A Minimally Invasive Method for Rare Orbital Tumor—Case Report and Review of Literature
title_short Endoscopic Endonasal Approach to Orbital Malignant Peripheral Nerve Sheath Tumor: A Minimally Invasive Method for Rare Orbital Tumor—Case Report and Review of Literature
title_sort endoscopic endonasal approach to orbital malignant peripheral nerve sheath tumor a minimally invasive method for rare orbital tumor case report and review of literature
topic MPNST
extremely rare
malignant
intraconal
endoscopic transnasal
gross total
url http://www.thieme-connect.de/DOI/DOI?10.1055/s-0043-1775973
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AT arijitchakraborty endoscopicendonasalapproachtoorbitalmalignantperipheralnervesheathtumoraminimallyinvasivemethodforrareorbitaltumorcasereportandreviewofliterature
AT kmbopanna endoscopicendonasalapproachtoorbitalmalignantperipheralnervesheathtumoraminimallyinvasivemethodforrareorbitaltumorcasereportandreviewofliterature
AT sathwikrshetty endoscopicendonasalapproachtoorbitalmalignantperipheralnervesheathtumoraminimallyinvasivemethodforrareorbitaltumorcasereportandreviewofliterature