Chaos and bifurcation analysis of tumor-immune controlled system with time delay

This paper establishes a delayed discrete tumor-immune model with feedback controller. The results indicate that the controlled system exhibits a trend from chaotic state to stability. The Flip bifurcation and Neimark–Sacker bifurcation of system are proved by the normal form method, central manifol...

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Main Authors: Danni Wang, Hongli Yang, Liangui Yang
Format: Article
Language:English
Published: Elsevier 2025-04-01
Series:Alexandria Engineering Journal
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1110016825001097
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author Danni Wang
Hongli Yang
Liangui Yang
author_facet Danni Wang
Hongli Yang
Liangui Yang
author_sort Danni Wang
collection DOAJ
description This paper establishes a delayed discrete tumor-immune model with feedback controller. The results indicate that the controlled system exhibits a trend from chaotic state to stability. The Flip bifurcation and Neimark–Sacker bifurcation of system are proved by the normal form method, central manifold theorem, and bifurcation theory. The Gram–Schmidt orthonormalization (GSO) method is used to interpret the attractor properties of uncontrolled and controlled systems, it is revealed that the attractors of controlled systems are smaller than those of uncontrolled systems, and the theoretical and numerical results are consistent. In addition, this research indicates that noise can cause significant changes in the amplitude of time-delay free system oscillations, with little impact on the period. Interestingly, the dynamic characteristics of noise in time-delay systems are not significantly affected by noise.
format Article
id doaj-art-6742d0595b9742ed94744328734fee00
institution Kabale University
issn 1110-0168
language English
publishDate 2025-04-01
publisher Elsevier
record_format Article
series Alexandria Engineering Journal
spelling doaj-art-6742d0595b9742ed94744328734fee002025-02-07T04:47:14ZengElsevierAlexandria Engineering Journal1110-01682025-04-01119267284Chaos and bifurcation analysis of tumor-immune controlled system with time delayDanni Wang0Hongli Yang1Liangui Yang2School of Mathematical Sciences, Inner Mongolia University, Hohhot 010021, ChinaCorresponding author.; School of Mathematical Sciences, Inner Mongolia University, Hohhot 010021, ChinaSchool of Mathematical Sciences, Inner Mongolia University, Hohhot 010021, ChinaThis paper establishes a delayed discrete tumor-immune model with feedback controller. The results indicate that the controlled system exhibits a trend from chaotic state to stability. The Flip bifurcation and Neimark–Sacker bifurcation of system are proved by the normal form method, central manifold theorem, and bifurcation theory. The Gram–Schmidt orthonormalization (GSO) method is used to interpret the attractor properties of uncontrolled and controlled systems, it is revealed that the attractors of controlled systems are smaller than those of uncontrolled systems, and the theoretical and numerical results are consistent. In addition, this research indicates that noise can cause significant changes in the amplitude of time-delay free system oscillations, with little impact on the period. Interestingly, the dynamic characteristics of noise in time-delay systems are not significantly affected by noise.http://www.sciencedirect.com/science/article/pii/S1110016825001097Chaos controlStabilityBifurcationTime delayNoise
spellingShingle Danni Wang
Hongli Yang
Liangui Yang
Chaos and bifurcation analysis of tumor-immune controlled system with time delay
Alexandria Engineering Journal
Chaos control
Stability
Bifurcation
Time delay
Noise
title Chaos and bifurcation analysis of tumor-immune controlled system with time delay
title_full Chaos and bifurcation analysis of tumor-immune controlled system with time delay
title_fullStr Chaos and bifurcation analysis of tumor-immune controlled system with time delay
title_full_unstemmed Chaos and bifurcation analysis of tumor-immune controlled system with time delay
title_short Chaos and bifurcation analysis of tumor-immune controlled system with time delay
title_sort chaos and bifurcation analysis of tumor immune controlled system with time delay
topic Chaos control
Stability
Bifurcation
Time delay
Noise
url http://www.sciencedirect.com/science/article/pii/S1110016825001097
work_keys_str_mv AT danniwang chaosandbifurcationanalysisoftumorimmunecontrolledsystemwithtimedelay
AT hongliyang chaosandbifurcationanalysisoftumorimmunecontrolledsystemwithtimedelay
AT lianguiyang chaosandbifurcationanalysisoftumorimmunecontrolledsystemwithtimedelay