The role of isoniazid dosage and NAT2 gene polymorphism in the treatment of tuberculous meningitis

The role of isoniazid dosage and NAT2 gene polymorphism in the treatment of tuberculous meningitis

BackgroundTuberculous meningitis (TBM) is a non-purulent inflammatory condition affecting the meninges and spinal membranes, caused by Mycobacterium tuberculosis (MTB) infection. This study seeks to explore the impact of varying INH dosages and NAT2 gene polymorphisms on TBM treatment, contributing...

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Bibliographic Details
Main Authors: Yi Jian, Yuhang Bao, Fashuang Yang, Mei Zhu
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-01-01
Series:Frontiers in Immunology
Subjects:
tuberculous meningitis
NAT2
isoniazid
treatment
prognosis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1535447/full
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