Chronic organophosphate-induced neuropsychiatric disorder: a case report

Shree Ram Ghimire,1 Sarita Parajuli2 1Department of Psychiatry, National Medical College, Birgunj, 2Department of Anesthesiology, Kathmandu National Medical College, Anamnagar, Kathmandu, Nepal Abstract: Chronic organophosphate (OP)-induced neuropsychiatric disorder is a rare condition following p...

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Main Authors: Ghimire SR, Parajuli S
Format: Article
Language:English
Published: Dove Medical Press 2016-02-01
Series:Neuropsychiatric Disease and Treatment
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Online Access:https://www.dovepress.com/chronic-organophosphate-induced-neuropsychiatric-disorder-a-case-repor-peer-reviewed-fulltext-article-NDT
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author Ghimire SR
Parajuli S
author_facet Ghimire SR
Parajuli S
author_sort Ghimire SR
collection DOAJ
description Shree Ram Ghimire,1 Sarita Parajuli2 1Department of Psychiatry, National Medical College, Birgunj, 2Department of Anesthesiology, Kathmandu National Medical College, Anamnagar, Kathmandu, Nepal Abstract: Chronic organophosphate (OP)-induced neuropsychiatric disorder is a rare condition following prolonged exposure to OP compounds. Due to the lack of valid diagnostic tools and criteria, very few cases are seen in clinical practice and are often misdiagnosed. Misdiagnosis can lead to inappropriate treatment that may increase the risk of morbidity or suicidality. In this paper, we present the case of a 35-year-old male who needed support in breathing from a mechanical ventilator and developed neuropsychiatric behavioral problems following ingestion of OP compounds, which lead to suicidality. The patient was treated by the psychiatric team with antipsychotic and antidepressants and improved following the regular use of medication. Keywords: COPIND, mood liability, suicidal thoughts
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series Neuropsychiatric Disease and Treatment
spelling doaj-art-672c59dacd5243ecbd59beb8ad32b1be2025-08-20T02:24:17ZengDove Medical PressNeuropsychiatric Disease and Treatment1178-20212016-02-01Volume 12Issue 127527725488Chronic organophosphate-induced neuropsychiatric disorder: a case reportGhimire SR0Parajuli SDepartment of PsychiatryShree Ram Ghimire,1 Sarita Parajuli2 1Department of Psychiatry, National Medical College, Birgunj, 2Department of Anesthesiology, Kathmandu National Medical College, Anamnagar, Kathmandu, Nepal Abstract: Chronic organophosphate (OP)-induced neuropsychiatric disorder is a rare condition following prolonged exposure to OP compounds. Due to the lack of valid diagnostic tools and criteria, very few cases are seen in clinical practice and are often misdiagnosed. Misdiagnosis can lead to inappropriate treatment that may increase the risk of morbidity or suicidality. In this paper, we present the case of a 35-year-old male who needed support in breathing from a mechanical ventilator and developed neuropsychiatric behavioral problems following ingestion of OP compounds, which lead to suicidality. The patient was treated by the psychiatric team with antipsychotic and antidepressants and improved following the regular use of medication. Keywords: COPIND, mood liability, suicidal thoughtshttps://www.dovepress.com/chronic-organophosphate-induced-neuropsychiatric-disorder-a-case-repor-peer-reviewed-fulltext-article-NDTCOPINDNeuropsychiatric disorderOrganophosphate compound
spellingShingle Ghimire SR
Parajuli S
Chronic organophosphate-induced neuropsychiatric disorder: a case report
Neuropsychiatric Disease and Treatment
COPIND
Neuropsychiatric disorder
Organophosphate compound
title Chronic organophosphate-induced neuropsychiatric disorder: a case report
title_full Chronic organophosphate-induced neuropsychiatric disorder: a case report
title_fullStr Chronic organophosphate-induced neuropsychiatric disorder: a case report
title_full_unstemmed Chronic organophosphate-induced neuropsychiatric disorder: a case report
title_short Chronic organophosphate-induced neuropsychiatric disorder: a case report
title_sort chronic organophosphate induced neuropsychiatric disorder a case report
topic COPIND
Neuropsychiatric disorder
Organophosphate compound
url https://www.dovepress.com/chronic-organophosphate-induced-neuropsychiatric-disorder-a-case-repor-peer-reviewed-fulltext-article-NDT
work_keys_str_mv AT ghimiresr chronicorganophosphateinducedneuropsychiatricdisorderacasereport
AT parajulis chronicorganophosphateinducedneuropsychiatricdisorderacasereport