Flap endonuclease 1 (FEN1) biomarker as a new diagnostic target for the biosensing of cancer

Flap endonuclease 1 (FEN1) biomarker as a new diagnostic target for the biosensing of cancer

Flap endonuclease 1 (FEN1) is a structure-specific nuclease that plays a role in DNA replication and genome stability. FEN1 is overexpressed in proliferative cancers and correlates with the grade and aggressiveness of the cancer, suggesting that it could potentially be considered a promising biomark...

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Bibliographic Details
Main Authors: Saba Mahboubi, Mehdi Evazalipour, Ehsan Zamani, Nozhat Zebardast, Alireza Farokhrouz, Rahim Nosrati
Format: Article
Language:English
Published: Elsevier 2025-06-01
Series:Sensors and Actuators Reports
Subjects:
Flap endonuclease 1 (FEN1)
Biosensor
Nanosensor
Cancer biomarker
CRISPR/Cas12a
Online Access:http://www.sciencedirect.com/science/article/pii/S2666053924000869
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