A Review of Factors Influencing the Banking of Collected Umbilical Cord Blood Units

Umbilical cord blood banking efforts have increased dramatically in the past two decades in response to increasing demand for alternative sources of blood stem cells to support patients requiring hematopoietic stem cell transplantation. Transplant centres have accumulated increasing expertise in the...

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Main Authors: David Allan, Tanya Petraszko, Heidi Elmoazzen, Susan Smith
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2013/463031
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author David Allan
Tanya Petraszko
Heidi Elmoazzen
Susan Smith
author_facet David Allan
Tanya Petraszko
Heidi Elmoazzen
Susan Smith
author_sort David Allan
collection DOAJ
description Umbilical cord blood banking efforts have increased dramatically in the past two decades in response to increasing demand for alternative sources of blood stem cells to support patients requiring hematopoietic stem cell transplantation. Transplant centres have accumulated increasing expertise in their understanding of umbilical cord blood characteristics that are associated with improved outcome following transplantation. These characteristics and factors can assist transplant centres in selecting cord blood units from the worldwide inventory of banked units. Umbilical cord blood banks, therefore, need to remain agile in adjusting the inventory of the banks to address shifts or changes in the needs of transplant centres. Public umbilical cord blood banks face the challenge of building inventory while managing limited resources and are faced with decisions regarding which units can be stored and which units that have been collected should be discarded or used for other endeavours such as research. To this end, we sought to review parameters influencing the decision to bank a collected cord blood unit. In this paper, we will address parameters associated with graft potency and address other factors that guide the decision to bank collected units.
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spelling doaj-art-671b4459a400461187967a973855ca0b2025-02-03T01:23:43ZengWileyStem Cells International1687-966X1687-96782013-01-01201310.1155/2013/463031463031A Review of Factors Influencing the Banking of Collected Umbilical Cord Blood UnitsDavid Allan0Tanya Petraszko1Heidi Elmoazzen2Susan Smith3Department of Medicine, Division of Hematology, University of Ottawa and Ottawa Hospital Research Institute, 501 Smyth Road, Box 701, Ottawa, ON, K1H 8L6, CanadaCanadian Blood Services, BC & Yukon Centre, 4750 Oak Street, Vancouver, BC, V6H 2N9, CanadaOneMatch, Canadian Blood Services, 1800 Alta Vista Drive, Ottawa, ON, K1G 4J5, CanadaOneMatch, Canadian Blood Services, 1800 Alta Vista Drive, Ottawa, ON, K1G 4J5, CanadaUmbilical cord blood banking efforts have increased dramatically in the past two decades in response to increasing demand for alternative sources of blood stem cells to support patients requiring hematopoietic stem cell transplantation. Transplant centres have accumulated increasing expertise in their understanding of umbilical cord blood characteristics that are associated with improved outcome following transplantation. These characteristics and factors can assist transplant centres in selecting cord blood units from the worldwide inventory of banked units. Umbilical cord blood banks, therefore, need to remain agile in adjusting the inventory of the banks to address shifts or changes in the needs of transplant centres. Public umbilical cord blood banks face the challenge of building inventory while managing limited resources and are faced with decisions regarding which units can be stored and which units that have been collected should be discarded or used for other endeavours such as research. To this end, we sought to review parameters influencing the decision to bank a collected cord blood unit. In this paper, we will address parameters associated with graft potency and address other factors that guide the decision to bank collected units.http://dx.doi.org/10.1155/2013/463031
spellingShingle David Allan
Tanya Petraszko
Heidi Elmoazzen
Susan Smith
A Review of Factors Influencing the Banking of Collected Umbilical Cord Blood Units
Stem Cells International
title A Review of Factors Influencing the Banking of Collected Umbilical Cord Blood Units
title_full A Review of Factors Influencing the Banking of Collected Umbilical Cord Blood Units
title_fullStr A Review of Factors Influencing the Banking of Collected Umbilical Cord Blood Units
title_full_unstemmed A Review of Factors Influencing the Banking of Collected Umbilical Cord Blood Units
title_short A Review of Factors Influencing the Banking of Collected Umbilical Cord Blood Units
title_sort review of factors influencing the banking of collected umbilical cord blood units
url http://dx.doi.org/10.1155/2013/463031
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