Therapeutic effects of hypoimmunogenic universal human iPSC-derived endothelial cells in a humanized mouse model of peripheral artery disease
Abstract Background Peripheral arterial disease (PAD) is a leading cause of limb disability due to ischemia caused by atherosclerotic plaques. Cell-based therapies using endothelial cells (ECs) have shown promise in promoting angiogenesis for PAD, but challenges remain in obtaining sufficient ECs fr...
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| Main Authors: | Jungju Choi, Nam Gyo Kim, Dasom Kong, Min-Ji Kim, Byeong-Cheol Kang, Daekee Kwon, Da-Hyun Kim, Kyung-Sun Kang |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2025-08-01
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| Series: | Stem Cell Research & Therapy |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13287-025-04554-5 |
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