Three cases of pseudoepitheliomatous hyperplasia mimicking squamous cell carcinoma of the foot: A case series

Pseudoepitheliomatous hyperplasia (PEH) is a benign condition characterized by hyperplasia and proliferation of the epidermis and adnexal epithelium which can mimic squamous cell carcinoma (SCC). In our first case, a 55-year-old female with a prior history of split skin graft presented with dark ver...

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Main Authors: M. Arulselvan, Trishna Vaishali Muthurathinam
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2024-01-01
Series:Journal of Current Research in Scientific Medicine
Subjects:
Online Access:https://journals.lww.com/10.4103/jcrsm.jcrsm_134_23
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author M. Arulselvan
Trishna Vaishali Muthurathinam
author_facet M. Arulselvan
Trishna Vaishali Muthurathinam
author_sort M. Arulselvan
collection DOAJ
description Pseudoepitheliomatous hyperplasia (PEH) is a benign condition characterized by hyperplasia and proliferation of the epidermis and adnexal epithelium which can mimic squamous cell carcinoma (SCC). In our first case, a 55-year-old female with a prior history of split skin graft presented with dark verrucous growth over the graft site with a nonhealing ulcer of 3 cm × 2 cm seen over the ventral aspect of the left foot. Our second case, a 59-year-old male with a prior history of split skin grafting presented with dark verrucous growth and pain over the right forefoot for 3 months. The third case, a 58-year-old man with diabetic foot ulcer with verrucous growth over the toes. In all the cases, the biopsy was done and diagnosed to be PEH. We report this case series of PEH for the proper distinction from the SCC of the skin.
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institution Kabale University
issn 2542-6273
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publishDate 2024-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Journal of Current Research in Scientific Medicine
spelling doaj-art-670228df02f24bc7b22c70420aaf57192025-01-23T05:27:12ZengWolters Kluwer Medknow PublicationsJournal of Current Research in Scientific Medicine2542-62732455-30692024-01-0110112412610.4103/jcrsm.jcrsm_134_23Three cases of pseudoepitheliomatous hyperplasia mimicking squamous cell carcinoma of the foot: A case seriesM. ArulselvanTrishna Vaishali MuthurathinamPseudoepitheliomatous hyperplasia (PEH) is a benign condition characterized by hyperplasia and proliferation of the epidermis and adnexal epithelium which can mimic squamous cell carcinoma (SCC). In our first case, a 55-year-old female with a prior history of split skin graft presented with dark verrucous growth over the graft site with a nonhealing ulcer of 3 cm × 2 cm seen over the ventral aspect of the left foot. Our second case, a 59-year-old male with a prior history of split skin grafting presented with dark verrucous growth and pain over the right forefoot for 3 months. The third case, a 58-year-old man with diabetic foot ulcer with verrucous growth over the toes. In all the cases, the biopsy was done and diagnosed to be PEH. We report this case series of PEH for the proper distinction from the SCC of the skin.https://journals.lww.com/10.4103/jcrsm.jcrsm_134_23biopsypseudoepitheliomatous hyperplasiasquamous cell carcinoma
spellingShingle M. Arulselvan
Trishna Vaishali Muthurathinam
Three cases of pseudoepitheliomatous hyperplasia mimicking squamous cell carcinoma of the foot: A case series
Journal of Current Research in Scientific Medicine
biopsy
pseudoepitheliomatous hyperplasia
squamous cell carcinoma
title Three cases of pseudoepitheliomatous hyperplasia mimicking squamous cell carcinoma of the foot: A case series
title_full Three cases of pseudoepitheliomatous hyperplasia mimicking squamous cell carcinoma of the foot: A case series
title_fullStr Three cases of pseudoepitheliomatous hyperplasia mimicking squamous cell carcinoma of the foot: A case series
title_full_unstemmed Three cases of pseudoepitheliomatous hyperplasia mimicking squamous cell carcinoma of the foot: A case series
title_short Three cases of pseudoepitheliomatous hyperplasia mimicking squamous cell carcinoma of the foot: A case series
title_sort three cases of pseudoepitheliomatous hyperplasia mimicking squamous cell carcinoma of the foot a case series
topic biopsy
pseudoepitheliomatous hyperplasia
squamous cell carcinoma
url https://journals.lww.com/10.4103/jcrsm.jcrsm_134_23
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AT trishnavaishalimuthurathinam threecasesofpseudoepitheliomatoushyperplasiamimickingsquamouscellcarcinomaofthefootacaseseries