Comparison of the effect of albumin with platelet-rich fibrin (Alb-PRF) gel and hyaluronic acid gel injection on interdental papilla reconstruction: A randomized clinical trial
Background. The interdental papilla plays a crucial role in the esthetic of the smile. Papilla reconstruction surgery is one of the most unpredictable periodontal procedures. This study compared the effect of the non-surgical application of a commercial hyaluronic acid (HA) gel with an autogenous ge...
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Tabriz University of Medical Sciences
2024-11-01
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| Series: | Journal of Advanced Periodontology and Implant Dentistry |
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| Online Access: | https://japid.tbzmed.ac.ir/PDF/japid-16-109.pdf |
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| author | Bardia Vadiati Saberi Ali Khalighi Sigaroudi Mobina Kamani Elahe Rafiei |
| author_facet | Bardia Vadiati Saberi Ali Khalighi Sigaroudi Mobina Kamani Elahe Rafiei |
| author_sort | Bardia Vadiati Saberi |
| collection | DOAJ |
| description | Background. The interdental papilla plays a crucial role in the esthetic of the smile. Papilla reconstruction surgery is one of the most unpredictable periodontal procedures. This study compared the effect of the non-surgical application of a commercial hyaluronic acid (HA) gel with an autogenous gel named "albumin with platelet-rich fibrin" (Alb-PRF) on interdental papilla reconstruction. Methods. This trial was conducted on 46 incomplete interdental papillae with class I or II defects. The papillae were randomly divided into two experimental groups, and commercial HA or Alb-PRF (prepared from the patient’s peripheral blood) was injected into the papillae twice at a 21-day interval. Three and six months after the intervention, photographs were taken from the black triangles and the black surfaces compared to each other. Patient satisfaction and dental plaque index were also evaluated at the end of the study. Results. The black triangles’ surfaces significantly decreased over time in both experimental groups (P<0.001). However, there were no significant differences between the two groups (P=0.994). The intervention resulted in the patients’ relative satisfaction with the treatment results in both groups. However, the difference between the two groups was not statistically significant (P=0.965). In addition, no statistically significant differences were observed in plaque index between the two groups (P=0.566). Conclusion. HA or Alb-PRF injection into the incomplete interdental papilla may restore the soft tissue to a great extent and lead to patient satisfaction by reducing the area of black triangles that threaten esthetics; however, more studies are needed. |
| format | Article |
| id | doaj-art-66f32b5919aa48c3a7947964ef62c1f1 |
| institution | OA Journals |
| issn | 2645-5390 |
| language | English |
| publishDate | 2024-11-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Journal of Advanced Periodontology and Implant Dentistry |
| spelling | doaj-art-66f32b5919aa48c3a7947964ef62c1f12025-08-20T02:17:13ZengTabriz University of Medical SciencesJournal of Advanced Periodontology and Implant Dentistry2645-53902024-11-0116210911510.34172/japid.2024.018japid-1228Comparison of the effect of albumin with platelet-rich fibrin (Alb-PRF) gel and hyaluronic acid gel injection on interdental papilla reconstruction: A randomized clinical trialBardia Vadiati Saberi0Ali Khalighi Sigaroudi1Mobina Kamani2Elahe Rafiei3Dental Sciences Research Center, Department of Periodontics, School of Dentistry, Guilan University of Medical Sciences, Rasht, IranDental Sciences Research Center, Department of Oral and Maxillofacial Surgery, School of Dentistry, Guilan University of Medical Sciences, Rasht, IranDepartment of Periodontics, School of Dentistry, Arak University of Medical Sciences, Arak, IranResearch and Technology, Guilan University of Medical Sciences, Rasht, IranBackground. The interdental papilla plays a crucial role in the esthetic of the smile. Papilla reconstruction surgery is one of the most unpredictable periodontal procedures. This study compared the effect of the non-surgical application of a commercial hyaluronic acid (HA) gel with an autogenous gel named "albumin with platelet-rich fibrin" (Alb-PRF) on interdental papilla reconstruction. Methods. This trial was conducted on 46 incomplete interdental papillae with class I or II defects. The papillae were randomly divided into two experimental groups, and commercial HA or Alb-PRF (prepared from the patient’s peripheral blood) was injected into the papillae twice at a 21-day interval. Three and six months after the intervention, photographs were taken from the black triangles and the black surfaces compared to each other. Patient satisfaction and dental plaque index were also evaluated at the end of the study. Results. The black triangles’ surfaces significantly decreased over time in both experimental groups (P<0.001). However, there were no significant differences between the two groups (P=0.994). The intervention resulted in the patients’ relative satisfaction with the treatment results in both groups. However, the difference between the two groups was not statistically significant (P=0.965). In addition, no statistically significant differences were observed in plaque index between the two groups (P=0.566). Conclusion. HA or Alb-PRF injection into the incomplete interdental papilla may restore the soft tissue to a great extent and lead to patient satisfaction by reducing the area of black triangles that threaten esthetics; however, more studies are needed.https://japid.tbzmed.ac.ir/PDF/japid-16-109.pdfblack trianglehyaluronic acidinterdental papilla reconstructionnon-surgical treatmentplatelet-rich fibrin |
| spellingShingle | Bardia Vadiati Saberi Ali Khalighi Sigaroudi Mobina Kamani Elahe Rafiei Comparison of the effect of albumin with platelet-rich fibrin (Alb-PRF) gel and hyaluronic acid gel injection on interdental papilla reconstruction: A randomized clinical trial Journal of Advanced Periodontology and Implant Dentistry black triangle hyaluronic acid interdental papilla reconstruction non-surgical treatment platelet-rich fibrin |
| title | Comparison of the effect of albumin with platelet-rich fibrin (Alb-PRF) gel and hyaluronic acid gel injection on interdental papilla reconstruction: A randomized clinical trial |
| title_full | Comparison of the effect of albumin with platelet-rich fibrin (Alb-PRF) gel and hyaluronic acid gel injection on interdental papilla reconstruction: A randomized clinical trial |
| title_fullStr | Comparison of the effect of albumin with platelet-rich fibrin (Alb-PRF) gel and hyaluronic acid gel injection on interdental papilla reconstruction: A randomized clinical trial |
| title_full_unstemmed | Comparison of the effect of albumin with platelet-rich fibrin (Alb-PRF) gel and hyaluronic acid gel injection on interdental papilla reconstruction: A randomized clinical trial |
| title_short | Comparison of the effect of albumin with platelet-rich fibrin (Alb-PRF) gel and hyaluronic acid gel injection on interdental papilla reconstruction: A randomized clinical trial |
| title_sort | comparison of the effect of albumin with platelet rich fibrin alb prf gel and hyaluronic acid gel injection on interdental papilla reconstruction a randomized clinical trial |
| topic | black triangle hyaluronic acid interdental papilla reconstruction non-surgical treatment platelet-rich fibrin |
| url | https://japid.tbzmed.ac.ir/PDF/japid-16-109.pdf |
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