Iodine-Induced Hyperthyroidism—An Old Clinical Entity That Is Still Relevant to Daily ICU Practice: A Case Report

Objective. Hyperthyroidism has been described as elevated serum free T3 and/or free T4 levels with decreased thyrotropin (TSH) concentrations. The main causes are related to autoimmune and neoplastic pathology. However, it might be caused due to a long-term topical exposure (iodine solution dressing...

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Main Authors: E. Brotfain, L. Koyfman, A. Frenkel, A. Smolikov, A. Zlotnik, M. Klein
Format: Article
Language:English
Published: Wiley 2013-01-01
Series:Case Reports in Endocrinology
Online Access:http://dx.doi.org/10.1155/2013/792745
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author E. Brotfain
L. Koyfman
A. Frenkel
A. Smolikov
A. Zlotnik
M. Klein
author_facet E. Brotfain
L. Koyfman
A. Frenkel
A. Smolikov
A. Zlotnik
M. Klein
author_sort E. Brotfain
collection DOAJ
description Objective. Hyperthyroidism has been described as elevated serum free T3 and/or free T4 levels with decreased thyrotropin (TSH) concentrations. The main causes are related to autoimmune and neoplastic pathology. However, it might be caused due to a long-term topical exposure (iodine solution dressing) or by intravenous administration of iodine-containing substances. Both clinical and laboratory features might be presented. The main management is based on interruption of all exposures with iodine solutions and also antithyroid medicine in case of severe laboratory and clinical disturbances. Data Sources. We present a case of iodine-induced hyperthyroidism in a critically ill ICU patient caused by excessive iodine containing antiseptic solution washes and contrast agent administration. The patient was successfully treated by discontinuing iodine exposure and beta-blocker administration. Conclusions. In patients with underlying thyroid gland pathology, thyroid-function tests and clinical observation in the ICU are of critical importance.
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spelling doaj-art-66f318f3cf2b4b57bec7ece151e2e9d62025-08-20T02:23:45ZengWileyCase Reports in Endocrinology2090-65012090-651X2013-01-01201310.1155/2013/792745792745Iodine-Induced Hyperthyroidism—An Old Clinical Entity That Is Still Relevant to Daily ICU Practice: A Case ReportE. Brotfain0L. Koyfman1A. Frenkel2A. Smolikov3A. Zlotnik4M. Klein5Department of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, Beer Sheva, IsraelDepartment of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, Beer Sheva, IsraelDepartment of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, Beer Sheva, IsraelDepartment of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, Beer Sheva, IsraelDepartment of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, Beer Sheva, IsraelDepartment of Anesthesiology and Critical Care, Soroka Medical Center, Ben-Gurion University of the Negev, Beer Sheva, IsraelObjective. Hyperthyroidism has been described as elevated serum free T3 and/or free T4 levels with decreased thyrotropin (TSH) concentrations. The main causes are related to autoimmune and neoplastic pathology. However, it might be caused due to a long-term topical exposure (iodine solution dressing) or by intravenous administration of iodine-containing substances. Both clinical and laboratory features might be presented. The main management is based on interruption of all exposures with iodine solutions and also antithyroid medicine in case of severe laboratory and clinical disturbances. Data Sources. We present a case of iodine-induced hyperthyroidism in a critically ill ICU patient caused by excessive iodine containing antiseptic solution washes and contrast agent administration. The patient was successfully treated by discontinuing iodine exposure and beta-blocker administration. Conclusions. In patients with underlying thyroid gland pathology, thyroid-function tests and clinical observation in the ICU are of critical importance.http://dx.doi.org/10.1155/2013/792745
spellingShingle E. Brotfain
L. Koyfman
A. Frenkel
A. Smolikov
A. Zlotnik
M. Klein
Iodine-Induced Hyperthyroidism—An Old Clinical Entity That Is Still Relevant to Daily ICU Practice: A Case Report
Case Reports in Endocrinology
title Iodine-Induced Hyperthyroidism—An Old Clinical Entity That Is Still Relevant to Daily ICU Practice: A Case Report
title_full Iodine-Induced Hyperthyroidism—An Old Clinical Entity That Is Still Relevant to Daily ICU Practice: A Case Report
title_fullStr Iodine-Induced Hyperthyroidism—An Old Clinical Entity That Is Still Relevant to Daily ICU Practice: A Case Report
title_full_unstemmed Iodine-Induced Hyperthyroidism—An Old Clinical Entity That Is Still Relevant to Daily ICU Practice: A Case Report
title_short Iodine-Induced Hyperthyroidism—An Old Clinical Entity That Is Still Relevant to Daily ICU Practice: A Case Report
title_sort iodine induced hyperthyroidism an old clinical entity that is still relevant to daily icu practice a case report
url http://dx.doi.org/10.1155/2013/792745
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AT asmolikov iodineinducedhyperthyroidismanoldclinicalentitythatisstillrelevanttodailyicupracticeacasereport
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