Psychiatric morbidity and quality of life in children and adolescents with cystic fibrosis

The aim of this study was to investigate psychiatric disorders, depression and anxiety levels, and quality of life in children and adolescents with cystic fibrosis (CF), and to compare them with those of children with non-cystic fibrosis (non-CF) bronchiectasis and healthy controls. A total of 103...

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Main Authors: Gülser Şenses-Dinç, Nural Kiper, Sevgi Pekcan, Ebru Çengel-Kültür, Ebru Yalçın, Esra Çöp, Deniz Doğru-Ersöz, Tuna Çak, Uğur Özçelik, Fatih Ünal
Format: Article
Language:English
Published: Hacettepe University Institute of Child Health 2018-02-01
Series:The Turkish Journal of Pediatrics
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Online Access:https://turkjpediatr.org/article/view/811
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author Gülser Şenses-Dinç
Nural Kiper
Sevgi Pekcan
Ebru Çengel-Kültür
Ebru Yalçın
Esra Çöp
Deniz Doğru-Ersöz
Tuna Çak
Uğur Özçelik
Fatih Ünal
author_facet Gülser Şenses-Dinç
Nural Kiper
Sevgi Pekcan
Ebru Çengel-Kültür
Ebru Yalçın
Esra Çöp
Deniz Doğru-Ersöz
Tuna Çak
Uğur Özçelik
Fatih Ünal
author_sort Gülser Şenses-Dinç
collection DOAJ
description The aim of this study was to investigate psychiatric disorders, depression and anxiety levels, and quality of life in children and adolescents with cystic fibrosis (CF), and to compare them with those of children with non-cystic fibrosis (non-CF) bronchiectasis and healthy controls. A total of 103 children and adolescents aged 7-16 years (35 CF, 28 non-CF bronchiectasis, 40 healthy) were evaluated using The Schedule for Affective Disorders and Schizophrenia for School Aged Children (K-SADS), The Child Depression Inventory (CDI), The State-Trait Anxiety Inventories for Children (STAI-C) and the Pediatric Quality of Life Inventory (PedsQL)-C. The three groups were not statistically different with respect to age, sex, and familial sociodemographic variables. 80% of the children and adolescents in the CF group were diagnosed with a psychiatric disorder, which was significantly more compared to those of the two other groups. The CF group had significantly greater rates of depressive and oppositional defiant disorder and the non-bronchiectasis group had a significantly greater rate of anxiety disorder than the control group. The depression and anxiety symptom levels were significantly greater and the quality of life levels significantly lower in both the CF and non-CF bronchiectasis groups than the healthy controls. In the CF group, the presence of any associated psychiatric disorder led to significantly lower total and psychosocial quality of life scores. In conclusion, CF is associated with poorer QOL in childhood. In order to improve quality of life in CF, the psychiatric conditions of children and adolescents should also be evaluated and their follow-up and treatment should involve a multidisciplinary team approach.
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publishDate 2018-02-01
publisher Hacettepe University Institute of Child Health
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spelling doaj-art-66ee2e6900c247e88d326bdd15ead7bb2025-08-20T02:55:38ZengHacettepe University Institute of Child HealthThe Turkish Journal of Pediatrics0041-43012791-64212018-02-0160110.24953/turkjped.2018.01.005Psychiatric morbidity and quality of life in children and adolescents with cystic fibrosisGülser Şenses-Dinç0Nural Kiper1Sevgi Pekcan2Ebru Çengel-Kültür3Ebru Yalçın4Esra Çöp5Deniz Doğru-Ersöz6Tuna Çak7Uğur Özçelik8Fatih Ünal9Clinics of Child and Adolescent Psychiatry, Ministry of Health Ankara Children's Health and Pediatric Hematology- Oncology Training and Research Hospital, , Ankara, Turkey.Departments of Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.Departments of Pediatric Pulmonology, Selcuk University Meram Faculty of Medicine, Konya, Turkey.Departments of Child and Adolescent Psychiatry, Hacettepe University Faculty of Medicine, Ankara, Turkey.Departments of Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.Clinics of Child and Adolescent Psychiatry, Ministry of Health Ankara Children's Health and Pediatric Hematology- Oncology Training and Research Hospital, , Ankara, Turkey.Departments of Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.Departments of Child and Adolescent Psychiatry, Hacettepe University Faculty of Medicine, Ankara, Turkey.Departments of Pulmonology, Hacettepe University Faculty of Medicine, Ankara, Turkey.Departments of Child and Adolescent Psychiatry, Hacettepe University Faculty of Medicine, Ankara, Turkey. The aim of this study was to investigate psychiatric disorders, depression and anxiety levels, and quality of life in children and adolescents with cystic fibrosis (CF), and to compare them with those of children with non-cystic fibrosis (non-CF) bronchiectasis and healthy controls. A total of 103 children and adolescents aged 7-16 years (35 CF, 28 non-CF bronchiectasis, 40 healthy) were evaluated using The Schedule for Affective Disorders and Schizophrenia for School Aged Children (K-SADS), The Child Depression Inventory (CDI), The State-Trait Anxiety Inventories for Children (STAI-C) and the Pediatric Quality of Life Inventory (PedsQL)-C. The three groups were not statistically different with respect to age, sex, and familial sociodemographic variables. 80% of the children and adolescents in the CF group were diagnosed with a psychiatric disorder, which was significantly more compared to those of the two other groups. The CF group had significantly greater rates of depressive and oppositional defiant disorder and the non-bronchiectasis group had a significantly greater rate of anxiety disorder than the control group. The depression and anxiety symptom levels were significantly greater and the quality of life levels significantly lower in both the CF and non-CF bronchiectasis groups than the healthy controls. In the CF group, the presence of any associated psychiatric disorder led to significantly lower total and psychosocial quality of life scores. In conclusion, CF is associated with poorer QOL in childhood. In order to improve quality of life in CF, the psychiatric conditions of children and adolescents should also be evaluated and their follow-up and treatment should involve a multidisciplinary team approach. https://turkjpediatr.org/article/view/811childrencystic fibrosispsychopathologyquality of life
spellingShingle Gülser Şenses-Dinç
Nural Kiper
Sevgi Pekcan
Ebru Çengel-Kültür
Ebru Yalçın
Esra Çöp
Deniz Doğru-Ersöz
Tuna Çak
Uğur Özçelik
Fatih Ünal
Psychiatric morbidity and quality of life in children and adolescents with cystic fibrosis
The Turkish Journal of Pediatrics
children
cystic fibrosis
psychopathology
quality of life
title Psychiatric morbidity and quality of life in children and adolescents with cystic fibrosis
title_full Psychiatric morbidity and quality of life in children and adolescents with cystic fibrosis
title_fullStr Psychiatric morbidity and quality of life in children and adolescents with cystic fibrosis
title_full_unstemmed Psychiatric morbidity and quality of life in children and adolescents with cystic fibrosis
title_short Psychiatric morbidity and quality of life in children and adolescents with cystic fibrosis
title_sort psychiatric morbidity and quality of life in children and adolescents with cystic fibrosis
topic children
cystic fibrosis
psychopathology
quality of life
url https://turkjpediatr.org/article/view/811
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AT ebrucengelkultur psychiatricmorbidityandqualityoflifeinchildrenandadolescentswithcysticfibrosis
AT ebruyalcın psychiatricmorbidityandqualityoflifeinchildrenandadolescentswithcysticfibrosis
AT esracop psychiatricmorbidityandqualityoflifeinchildrenandadolescentswithcysticfibrosis
AT denizdogruersoz psychiatricmorbidityandqualityoflifeinchildrenandadolescentswithcysticfibrosis
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