Dynamics of blood osteomarkers in the treatment of generalized periodontitis

AIM. Study of the dynamics of bone metabolism in the treatment of generalized periodontitis.MATERIALS AND METHODS. 60 patients with chronic generalized periodontitis of moderate to severe severity were examined and treated. A group of 15 healthy individuals without periodontal disease served as a co...

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Main Authors: O. A. Uspenskaya, E. S. Kachesova, A. I. Mednikova, R. A. Ftoyan
Format: Article
Language:Russian
Published: LLC "Endo Press" 2024-06-01
Series:Эндодонтия Today
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Online Access:https://www.endodont.ru/jour/article/view/1306
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author O. A. Uspenskaya
E. S. Kachesova
A. I. Mednikova
R. A. Ftoyan
author_facet O. A. Uspenskaya
E. S. Kachesova
A. I. Mednikova
R. A. Ftoyan
author_sort O. A. Uspenskaya
collection DOAJ
description AIM. Study of the dynamics of bone metabolism in the treatment of generalized periodontitis.MATERIALS AND METHODS. 60 patients with chronic generalized periodontitis of moderate to severe severity were examined and treated. A group of 15 healthy individuals without periodontal disease served as a control group. To assess the dynamics of bone formation, blood parameters were measured for bone metabolism: osteocalcin levels, alkaline phosphatase levels, and β-CrossLaps levels. Densitometry of the proximal femoral and lumbar spine regions was also performed.RESULTS. The study revealed increased bone metabolism compared with the control group, an increase in bone metabolism activity was found 3 months after treatment of patients with chronic generalized periodontitis, and after 12 months the values of the studied parameters did not differ from the control group.CONCLUSIONS. Thus, when treating generalized periodontitis, it is necessary to use a treatment regimen that takes into account the individual mineral metabolism of the patient’s bone tissue.
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institution Kabale University
issn 1683-2981
1726-7242
language Russian
publishDate 2024-06-01
publisher LLC "Endo Press"
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series Эндодонтия Today
spelling doaj-art-66d28efea0b74d0e9b9adc24315cd4ee2025-08-20T03:40:06ZrusLLC "Endo Press"Эндодонтия Today1683-29811726-72422024-06-0122216216610.36377/ET-00211077Dynamics of blood osteomarkers in the treatment of generalized periodontitisO. A. Uspenskaya0E. S. Kachesova1A. I. Mednikova2R. A. Ftoyan3Privolzhsky Research Medical UniversityPrivolzhsky Research Medical UniversityPrivolzhsky Research Medical UniversityPrivolzhsky Research Medical UniversityAIM. Study of the dynamics of bone metabolism in the treatment of generalized periodontitis.MATERIALS AND METHODS. 60 patients with chronic generalized periodontitis of moderate to severe severity were examined and treated. A group of 15 healthy individuals without periodontal disease served as a control group. To assess the dynamics of bone formation, blood parameters were measured for bone metabolism: osteocalcin levels, alkaline phosphatase levels, and β-CrossLaps levels. Densitometry of the proximal femoral and lumbar spine regions was also performed.RESULTS. The study revealed increased bone metabolism compared with the control group, an increase in bone metabolism activity was found 3 months after treatment of patients with chronic generalized periodontitis, and after 12 months the values of the studied parameters did not differ from the control group.CONCLUSIONS. Thus, when treating generalized periodontitis, it is necessary to use a treatment regimen that takes into account the individual mineral metabolism of the patient’s bone tissue.https://www.endodont.ru/jour/article/view/1306chronic generalized periodontitisosteocalcinalkaline phosphatasebone metabolismβ-crosslaps
spellingShingle O. A. Uspenskaya
E. S. Kachesova
A. I. Mednikova
R. A. Ftoyan
Dynamics of blood osteomarkers in the treatment of generalized periodontitis
Эндодонтия Today
chronic generalized periodontitis
osteocalcin
alkaline phosphatase
bone metabolism
β-crosslaps
title Dynamics of blood osteomarkers in the treatment of generalized periodontitis
title_full Dynamics of blood osteomarkers in the treatment of generalized periodontitis
title_fullStr Dynamics of blood osteomarkers in the treatment of generalized periodontitis
title_full_unstemmed Dynamics of blood osteomarkers in the treatment of generalized periodontitis
title_short Dynamics of blood osteomarkers in the treatment of generalized periodontitis
title_sort dynamics of blood osteomarkers in the treatment of generalized periodontitis
topic chronic generalized periodontitis
osteocalcin
alkaline phosphatase
bone metabolism
β-crosslaps
url https://www.endodont.ru/jour/article/view/1306
work_keys_str_mv AT oauspenskaya dynamicsofbloodosteomarkersinthetreatmentofgeneralizedperiodontitis
AT eskachesova dynamicsofbloodosteomarkersinthetreatmentofgeneralizedperiodontitis
AT aimednikova dynamicsofbloodosteomarkersinthetreatmentofgeneralizedperiodontitis
AT raftoyan dynamicsofbloodosteomarkersinthetreatmentofgeneralizedperiodontitis