PROGNOSTIC SIGNIFICANCE OF GALECTIN-3 LEVEL ASSESSMENT IN METABOLIC SYNDROME PATIENTS WITH HEART FAILURE
Aim. To assess the level of galectin-3 in blood serum of metabolic syndrome patients (MS), with heart failure (CHF).Material and methods. Totally, 43 patients investigated, with MS, and of those 37 CHF patients and 33 on-CHF, of those 17 had CHF diagnosed. Galectin-3 level in blood serum was measure...
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«SILICEA-POLIGRAF» LLC
2017-12-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/626 |
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| author | O. M. Drapkina R. N. Shepel T. A. Deeva |
| author_facet | O. M. Drapkina R. N. Shepel T. A. Deeva |
| author_sort | O. M. Drapkina |
| collection | DOAJ |
| description | Aim. To assess the level of galectin-3 in blood serum of metabolic syndrome patients (MS), with heart failure (CHF).Material and methods. Totally, 43 patients investigated, with MS, and of those 37 CHF patients and 33 on-CHF, of those 17 had CHF diagnosed. Galectin-3 level in blood serum was measured by immune enzyme assay.Results. Galectin-3 level in blood plasma of MS patients was significantly higher comparing to the group with no MS — 1,89±1,71 ng/mL and 1,03±0,22 ng/mL, respectively. In the control group maximum galectin-3 level was 1,5 ng/mL, but in MS group 27% had galectin-3 higher than 3 ng/mL. It was found that mean levels of galectin-3 were significantly higher in CHF group (1,73±1,59 ng/mL) comparing to non-CHF (1,05±0,26 ng/mL).Conclusion. Level of galectin-3 in MS patients is higher than in those non-MS, but in MS and CHF galectin-3 concentration is higher than nonCHF. Further elaboration on this relationship might be useful in improvement of CHD and MS diagnostics. |
| format | Article |
| id | doaj-art-66d22f6d1b7942ec93f0bfaa07b13caf |
| institution | Kabale University |
| issn | 1728-8800 2619-0125 |
| language | Russian |
| publishDate | 2017-12-01 |
| publisher | «SILICEA-POLIGRAF» LLC |
| record_format | Article |
| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj-art-66d22f6d1b7942ec93f0bfaa07b13caf2025-08-20T03:35:47Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252017-12-01166828610.15829/1728-8800-2017-6-82-86499PROGNOSTIC SIGNIFICANCE OF GALECTIN-3 LEVEL ASSESSMENT IN METABOLIC SYNDROME PATIENTS WITH HEART FAILUREO. M. Drapkina0R. N. Shepel1T. A. Deeva2National Research Center for Preventive Medicine of the Ministry of HealthNational Research Center for Preventive Medicine of the Ministry of HealthI.M. Sechenov First Moscow State Medical University of the Ministry of HealthAim. To assess the level of galectin-3 in blood serum of metabolic syndrome patients (MS), with heart failure (CHF).Material and methods. Totally, 43 patients investigated, with MS, and of those 37 CHF patients and 33 on-CHF, of those 17 had CHF diagnosed. Galectin-3 level in blood serum was measured by immune enzyme assay.Results. Galectin-3 level in blood plasma of MS patients was significantly higher comparing to the group with no MS — 1,89±1,71 ng/mL and 1,03±0,22 ng/mL, respectively. In the control group maximum galectin-3 level was 1,5 ng/mL, but in MS group 27% had galectin-3 higher than 3 ng/mL. It was found that mean levels of galectin-3 were significantly higher in CHF group (1,73±1,59 ng/mL) comparing to non-CHF (1,05±0,26 ng/mL).Conclusion. Level of galectin-3 in MS patients is higher than in those non-MS, but in MS and CHF galectin-3 concentration is higher than nonCHF. Further elaboration on this relationship might be useful in improvement of CHD and MS diagnostics.https://cardiovascular.elpub.ru/jour/article/view/626galectin-3metabolic syndromechronic heart failure |
| spellingShingle | O. M. Drapkina R. N. Shepel T. A. Deeva PROGNOSTIC SIGNIFICANCE OF GALECTIN-3 LEVEL ASSESSMENT IN METABOLIC SYNDROME PATIENTS WITH HEART FAILURE Кардиоваскулярная терапия и профилактика galectin-3 metabolic syndrome chronic heart failure |
| title | PROGNOSTIC SIGNIFICANCE OF GALECTIN-3 LEVEL ASSESSMENT IN METABOLIC SYNDROME PATIENTS WITH HEART FAILURE |
| title_full | PROGNOSTIC SIGNIFICANCE OF GALECTIN-3 LEVEL ASSESSMENT IN METABOLIC SYNDROME PATIENTS WITH HEART FAILURE |
| title_fullStr | PROGNOSTIC SIGNIFICANCE OF GALECTIN-3 LEVEL ASSESSMENT IN METABOLIC SYNDROME PATIENTS WITH HEART FAILURE |
| title_full_unstemmed | PROGNOSTIC SIGNIFICANCE OF GALECTIN-3 LEVEL ASSESSMENT IN METABOLIC SYNDROME PATIENTS WITH HEART FAILURE |
| title_short | PROGNOSTIC SIGNIFICANCE OF GALECTIN-3 LEVEL ASSESSMENT IN METABOLIC SYNDROME PATIENTS WITH HEART FAILURE |
| title_sort | prognostic significance of galectin 3 level assessment in metabolic syndrome patients with heart failure |
| topic | galectin-3 metabolic syndrome chronic heart failure |
| url | https://cardiovascular.elpub.ru/jour/article/view/626 |
| work_keys_str_mv | AT omdrapkina prognosticsignificanceofgalectin3levelassessmentinmetabolicsyndromepatientswithheartfailure AT rnshepel prognosticsignificanceofgalectin3levelassessmentinmetabolicsyndromepatientswithheartfailure AT tadeeva prognosticsignificanceofgalectin3levelassessmentinmetabolicsyndromepatientswithheartfailure |