Incidence rate of postoperative cognitive dysfunction at different anesthetic depths and its correlation with serum levels of RAGE, NR2B, CREB, and NFL
Anesthetic depth may affect cognitive function, which is reflected by serum biomarker levels. We aimed to investigate the incidence rate of postoperative cognitive dysfunction (POCD) at different anesthetic depths and its correlations with levels of serum receptor for advanced glycation end product...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Sciendo
2025-04-01
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| Series: | Romanian Journal of Laboratory Medicine |
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| Online Access: | https://doi.org/10.2478/rrlm-2025-0009 |
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| _version_ | 1849325717995651072 |
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| author | Yang Xuegang Lin Xuhe Chen Qingjuan Zhang Wenwen |
| author_facet | Yang Xuegang Lin Xuhe Chen Qingjuan Zhang Wenwen |
| author_sort | Yang Xuegang |
| collection | DOAJ |
| description | Anesthetic depth may affect cognitive function, which is reflected by serum biomarker levels. We aimed to investigate the incidence rate of postoperative cognitive dysfunction (POCD) at different anesthetic depths and its correlations with levels of serum receptor for advanced glycation end product (RAGE), N-methyl-D-aspartate receptor 2B subunit (NR2B), cAMP response element-binding protein (CREB) and neurofilament light chain (NFL). |
| format | Article |
| id | doaj-art-66cdd1a1639e42d4bef575ad967b2dae |
| institution | Kabale University |
| issn | 2284-5623 |
| language | English |
| publishDate | 2025-04-01 |
| publisher | Sciendo |
| record_format | Article |
| series | Romanian Journal of Laboratory Medicine |
| spelling | doaj-art-66cdd1a1639e42d4bef575ad967b2dae2025-08-20T03:48:19ZengSciendoRomanian Journal of Laboratory Medicine2284-56232025-04-01332879410.2478/rrlm-2025-0009Incidence rate of postoperative cognitive dysfunction at different anesthetic depths and its correlation with serum levels of RAGE, NR2B, CREB, and NFLYang Xuegang0Lin Xuhe1Chen Qingjuan2Zhang Wenwen31Department of Anesthesiology, Lin'an District Traditional Chinese Medicine Hospital, Hangzhou, Zhejiang Province, China2Department of Anesthesiology, Shantou Chenghai People’s Hospital, Shantou, Guangdong Province, China3Department of Anesthesiology, Taizhou Hospital of Zhejiang Province affiliated to Wenzhou Medical University, Taizhou, Zhejiang Province, China4Department of Anesthesiology, Yinzhou No. 2 Hospital, Ningbo, Zhejiang Province, ChinaAnesthetic depth may affect cognitive function, which is reflected by serum biomarker levels. We aimed to investigate the incidence rate of postoperative cognitive dysfunction (POCD) at different anesthetic depths and its correlations with levels of serum receptor for advanced glycation end product (RAGE), N-methyl-D-aspartate receptor 2B subunit (NR2B), cAMP response element-binding protein (CREB) and neurofilament light chain (NFL).https://doi.org/10.2478/rrlm-2025-0009cognitive dysfunctiondepthgeneral anesthesiaincidenceserum biomarker |
| spellingShingle | Yang Xuegang Lin Xuhe Chen Qingjuan Zhang Wenwen Incidence rate of postoperative cognitive dysfunction at different anesthetic depths and its correlation with serum levels of RAGE, NR2B, CREB, and NFL Romanian Journal of Laboratory Medicine cognitive dysfunction depth general anesthesia incidence serum biomarker |
| title | Incidence rate of postoperative cognitive dysfunction at different anesthetic depths and its correlation with serum levels of RAGE, NR2B, CREB, and NFL |
| title_full | Incidence rate of postoperative cognitive dysfunction at different anesthetic depths and its correlation with serum levels of RAGE, NR2B, CREB, and NFL |
| title_fullStr | Incidence rate of postoperative cognitive dysfunction at different anesthetic depths and its correlation with serum levels of RAGE, NR2B, CREB, and NFL |
| title_full_unstemmed | Incidence rate of postoperative cognitive dysfunction at different anesthetic depths and its correlation with serum levels of RAGE, NR2B, CREB, and NFL |
| title_short | Incidence rate of postoperative cognitive dysfunction at different anesthetic depths and its correlation with serum levels of RAGE, NR2B, CREB, and NFL |
| title_sort | incidence rate of postoperative cognitive dysfunction at different anesthetic depths and its correlation with serum levels of rage nr2b creb and nfl |
| topic | cognitive dysfunction depth general anesthesia incidence serum biomarker |
| url | https://doi.org/10.2478/rrlm-2025-0009 |
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