Plasma Leptin Concentrations and Esophageal Hypomotility in Obese Patients

BACKGROUND: Although esophageal hypomotility is prevalent in obese patients, its cause remains unknown. Leptin, a hormone derived from adipose tissue, may be involved in this phenomenon because it has been shown to decrease gastric and intestinal motility in animals. It has been hypothesized that el...

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Main Authors: Justin Côté-Daigneault, Pierre Poitras, Rémi Rabasa-Lhoret, Mickael Bouin
Format: Article
Language:English
Published: Wiley 2015-01-01
Series:Canadian Journal of Gastroenterology and Hepatology
Online Access:http://dx.doi.org/10.1155/2015/490818
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author Justin Côté-Daigneault
Pierre Poitras
Rémi Rabasa-Lhoret
Mickael Bouin
author_facet Justin Côté-Daigneault
Pierre Poitras
Rémi Rabasa-Lhoret
Mickael Bouin
author_sort Justin Côté-Daigneault
collection DOAJ
description BACKGROUND: Although esophageal hypomotility is prevalent in obese patients, its cause remains unknown. Leptin, a hormone derived from adipose tissue, may be involved in this phenomenon because it has been shown to decrease gastric and intestinal motility in animals. It has been hypothesized that elevated plasma leptin concentration is a risk factor for esophageal dysmotility in obese patients.
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institution Kabale University
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publishDate 2015-01-01
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series Canadian Journal of Gastroenterology and Hepatology
spelling doaj-art-66c4597ea39a4cab891780fa14de21cc2025-02-03T05:58:46ZengWileyCanadian Journal of Gastroenterology and Hepatology2291-27892291-27972015-01-01291495110.1155/2015/490818Plasma Leptin Concentrations and Esophageal Hypomotility in Obese PatientsJustin Côté-Daigneault0Pierre Poitras1Rémi Rabasa-Lhoret2Mickael Bouin3Department of Gastroenterology, Centre Hospitalier de l’Université de Montréal (CHUM), CanadaDepartment of Gastroenterology, Centre Hospitalier de l’Université de Montréal (CHUM), CanadaDepartment of Endocrinology, Centre Hospitalier de l’Université de Montréal (CHUM), CanadaDepartment of Gastroenterology, Centre Hospitalier de l’Université de Montréal (CHUM), CanadaBACKGROUND: Although esophageal hypomotility is prevalent in obese patients, its cause remains unknown. Leptin, a hormone derived from adipose tissue, may be involved in this phenomenon because it has been shown to decrease gastric and intestinal motility in animals. It has been hypothesized that elevated plasma leptin concentration is a risk factor for esophageal dysmotility in obese patients.http://dx.doi.org/10.1155/2015/490818
spellingShingle Justin Côté-Daigneault
Pierre Poitras
Rémi Rabasa-Lhoret
Mickael Bouin
Plasma Leptin Concentrations and Esophageal Hypomotility in Obese Patients
Canadian Journal of Gastroenterology and Hepatology
title Plasma Leptin Concentrations and Esophageal Hypomotility in Obese Patients
title_full Plasma Leptin Concentrations and Esophageal Hypomotility in Obese Patients
title_fullStr Plasma Leptin Concentrations and Esophageal Hypomotility in Obese Patients
title_full_unstemmed Plasma Leptin Concentrations and Esophageal Hypomotility in Obese Patients
title_short Plasma Leptin Concentrations and Esophageal Hypomotility in Obese Patients
title_sort plasma leptin concentrations and esophageal hypomotility in obese patients
url http://dx.doi.org/10.1155/2015/490818
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AT pierrepoitras plasmaleptinconcentrationsandesophagealhypomotilityinobesepatients
AT remirabasalhoret plasmaleptinconcentrationsandesophagealhypomotilityinobesepatients
AT mickaelbouin plasmaleptinconcentrationsandesophagealhypomotilityinobesepatients