THE SELECTION PROBLEMS OF ANTITHROMBOTIC THERAPY IN NONVALVULAR ATRIAL FIBRILLATION WITH COMORBIDITIES

As does the clinical practice show, physician often deals with a problem of intolerability of oral anticoagulants, both vitamin K antagonists and new oral anticoagulants, either with a refuse taking these drugs at all. Hence there is an issue raises on the selection of antithrombotic therapy in atri...

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Main Authors: N. A. Koziolova, Е. А. Polyanskaya
Format: Article
Language:Russian
Published: «SILICEA-POLIGRAF» LLC 2015-08-01
Series:Кардиоваскулярная терапия и профилактика
Subjects:
Online Access:https://cardiovascular.elpub.ru/jour/article/view/250
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author N. A. Koziolova
Е. А. Polyanskaya
author_facet N. A. Koziolova
Е. А. Polyanskaya
author_sort N. A. Koziolova
collection DOAJ
description As does the clinical practice show, physician often deals with a problem of intolerability of oral anticoagulants, both vitamin K antagonists and new oral anticoagulants, either with a refuse taking these drugs at all. Hence there is an issue raises on the selection of antithrombotic therapy in atrial fibrillation (AF), and primarily, with ischemic heart disease, diabetes, stroke in anamnesis. There is a broad discussion in literature of the purpose for prescription of aspirin monotherapy to such patients with the aim of myocardial infarction and ischemic stroke prevention. In the article we present a case of female patient with nonvalvular AF having ischemic stroke and acute coronary syndrome at the background of serious comorbidities, the errors in the management are shown on the selection of antithrombotic therapy and directions provided for secondary prevention of thromboembolic complications, recurrent ischemic events according to International and Russian Guidelines.
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series Кардиоваскулярная терапия и профилактика
spelling doaj-art-66bcf03f1ba84b4887e98db5ac37f2ca2025-08-20T03:57:17Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252015-08-01144758510.15829/1728-8800-2015-4-75-85249THE SELECTION PROBLEMS OF ANTITHROMBOTIC THERAPY IN NONVALVULAR ATRIAL FIBRILLATION WITH COMORBIDITIESN. A. Koziolova0Е. А. Polyanskaya1SBEI HPE "Perm State Medical University n.a. E. A. Wagner" of the Healthcare Ministry. Perm, RussiaSBEI HPE "Perm State Medical University n.a. E. A. Wagner" of the Healthcare Ministry. Perm, RussiaAs does the clinical practice show, physician often deals with a problem of intolerability of oral anticoagulants, both vitamin K antagonists and new oral anticoagulants, either with a refuse taking these drugs at all. Hence there is an issue raises on the selection of antithrombotic therapy in atrial fibrillation (AF), and primarily, with ischemic heart disease, diabetes, stroke in anamnesis. There is a broad discussion in literature of the purpose for prescription of aspirin monotherapy to such patients with the aim of myocardial infarction and ischemic stroke prevention. In the article we present a case of female patient with nonvalvular AF having ischemic stroke and acute coronary syndrome at the background of serious comorbidities, the errors in the management are shown on the selection of antithrombotic therapy and directions provided for secondary prevention of thromboembolic complications, recurrent ischemic events according to International and Russian Guidelines.https://cardiovascular.elpub.ru/jour/article/view/250atrial fibrillationanticoagulantsacetylsalicylic acidclopidogrel
spellingShingle N. A. Koziolova
Е. А. Polyanskaya
THE SELECTION PROBLEMS OF ANTITHROMBOTIC THERAPY IN NONVALVULAR ATRIAL FIBRILLATION WITH COMORBIDITIES
Кардиоваскулярная терапия и профилактика
atrial fibrillation
anticoagulants
acetylsalicylic acid
clopidogrel
title THE SELECTION PROBLEMS OF ANTITHROMBOTIC THERAPY IN NONVALVULAR ATRIAL FIBRILLATION WITH COMORBIDITIES
title_full THE SELECTION PROBLEMS OF ANTITHROMBOTIC THERAPY IN NONVALVULAR ATRIAL FIBRILLATION WITH COMORBIDITIES
title_fullStr THE SELECTION PROBLEMS OF ANTITHROMBOTIC THERAPY IN NONVALVULAR ATRIAL FIBRILLATION WITH COMORBIDITIES
title_full_unstemmed THE SELECTION PROBLEMS OF ANTITHROMBOTIC THERAPY IN NONVALVULAR ATRIAL FIBRILLATION WITH COMORBIDITIES
title_short THE SELECTION PROBLEMS OF ANTITHROMBOTIC THERAPY IN NONVALVULAR ATRIAL FIBRILLATION WITH COMORBIDITIES
title_sort selection problems of antithrombotic therapy in nonvalvular atrial fibrillation with comorbidities
topic atrial fibrillation
anticoagulants
acetylsalicylic acid
clopidogrel
url https://cardiovascular.elpub.ru/jour/article/view/250
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AT nakoziolova selectionproblemsofantithrombotictherapyinnonvalvularatrialfibrillationwithcomorbidities
AT eapolyanskaya selectionproblemsofantithrombotictherapyinnonvalvularatrialfibrillationwithcomorbidities