Review in green synthesis mechanisms, application, and future prospects for Garcinia mangostana L. (mangosteen)-derived nanoparticles

The growing global demand for sustainable and cost-effective methods of nanomaterial production has driven the development of green synthesis techniques, offering a safer alternative to traditional, hazardous approaches. Among the numerous plants utilized for this purpose, Garcinia mangostana L. (ma...

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Main Authors: Chan Yu Bin, Aminuzzaman Mohammod, Chuah Xinn-Tze, Li Kefeng, Balu Prakash, Wong Ling Shing, Guha Samar Kumar, Tey Lai-Hock
Format: Article
Language:English
Published: De Gruyter 2025-04-01
Series:Nanotechnology Reviews
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Online Access:https://doi.org/10.1515/ntrev-2025-0157
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author Chan Yu Bin
Aminuzzaman Mohammod
Chuah Xinn-Tze
Li Kefeng
Balu Prakash
Wong Ling Shing
Guha Samar Kumar
Tey Lai-Hock
author_facet Chan Yu Bin
Aminuzzaman Mohammod
Chuah Xinn-Tze
Li Kefeng
Balu Prakash
Wong Ling Shing
Guha Samar Kumar
Tey Lai-Hock
author_sort Chan Yu Bin
collection DOAJ
description The growing global demand for sustainable and cost-effective methods of nanomaterial production has driven the development of green synthesis techniques, offering a safer alternative to traditional, hazardous approaches. Among the numerous plants utilized for this purpose, Garcinia mangostana L. (mangosteen) stands out due to its high content of bioactive phytochemicals, such as α-mangostin, xanthones, and other secondary metabolites. These compounds serve as natural reducing, capping, and stabilizing agents in the synthesis of metal and metal oxide nanoparticles (NPs) such as silver, gold, and zinc oxide. In contrast to traditional approaches reliant on toxic chemicals and harsh circumstances, mangosteen extracts facilitate the production of NPs in moderate and sustainable conditions, offering a viable strategy for sustainable nanotechnology. This review article offers a thorough examination of the green synthesis processes utilizing extracts from mangosteen, going over the physicochemical characteristics of the resultant NPs and their numerous uses, such as antimicrobial and anticancer properties, antioxidant therapy, and environmental remediation. It is highlighted that NPs synthesized from mangosteen have the potential to solve environmental and health issues. However, to enable wider industrial and commercial applications, important issues including scalability, repeatability of NP properties, and long-term stability need to be addressed. In addition to providing insights into the creation of sustainable NPs, this study critically evaluates existing research and lays the groundwork for future developments in green nanotechnology.
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spelling doaj-art-66b4d8af412c44719de2a0bd0f0678482025-08-20T03:11:07ZengDe GruyterNanotechnology Reviews2191-90972025-04-01141103013610.1515/ntrev-2025-0157Review in green synthesis mechanisms, application, and future prospects for Garcinia mangostana L. (mangosteen)-derived nanoparticlesChan Yu Bin0Aminuzzaman Mohammod1Chuah Xinn-Tze2Li Kefeng3Balu Prakash4Wong Ling Shing5Guha Samar Kumar6Tey Lai-Hock7Department of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman (UTAR), Kampar Campus, Kampar, 31900, Perak, MalaysiaDepartment of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman (UTAR), Kampar Campus, Kampar, 31900, Perak, MalaysiaDepartment of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman (UTAR), Kampar Campus, Kampar, 31900, Perak, MalaysiaFaculty of Applied Sciences, Macau Polytechnic University, R. de Luís Gonzaga Gomes, 999078, Macao, ChinaDepartment of Biotechnology, Vels Institute of Science, Technology and Advanced Studies (VISTAS), Velan Nagar, P.V. Vaithiyalingam Road, Pallavaram, Chennai, 600 117, Tamil Nadu, IndiaFaculty of Health and Life Sciences, INTI International University, Nilai, 71800, Negeri Sembilan, MalaysiaDepartment of Arts and Sciences, Faculty of Engineering, Ahsanullah University of Science and Technology, 141-142, Love Road, Tejgaon I/A, Dhaka, 1208, BangladeshDepartment of Chemical Science, Faculty of Science, Universiti Tunku Abdul Rahman (UTAR), Kampar Campus, Kampar, 31900, Perak, MalaysiaThe growing global demand for sustainable and cost-effective methods of nanomaterial production has driven the development of green synthesis techniques, offering a safer alternative to traditional, hazardous approaches. Among the numerous plants utilized for this purpose, Garcinia mangostana L. (mangosteen) stands out due to its high content of bioactive phytochemicals, such as α-mangostin, xanthones, and other secondary metabolites. These compounds serve as natural reducing, capping, and stabilizing agents in the synthesis of metal and metal oxide nanoparticles (NPs) such as silver, gold, and zinc oxide. In contrast to traditional approaches reliant on toxic chemicals and harsh circumstances, mangosteen extracts facilitate the production of NPs in moderate and sustainable conditions, offering a viable strategy for sustainable nanotechnology. This review article offers a thorough examination of the green synthesis processes utilizing extracts from mangosteen, going over the physicochemical characteristics of the resultant NPs and their numerous uses, such as antimicrobial and anticancer properties, antioxidant therapy, and environmental remediation. It is highlighted that NPs synthesized from mangosteen have the potential to solve environmental and health issues. However, to enable wider industrial and commercial applications, important issues including scalability, repeatability of NP properties, and long-term stability need to be addressed. In addition to providing insights into the creation of sustainable NPs, this study critically evaluates existing research and lays the groundwork for future developments in green nanotechnology.https://doi.org/10.1515/ntrev-2025-0157green synthesisnanomaterialsplant extractsgarcinia mangostana l.phytochemicals
spellingShingle Chan Yu Bin
Aminuzzaman Mohammod
Chuah Xinn-Tze
Li Kefeng
Balu Prakash
Wong Ling Shing
Guha Samar Kumar
Tey Lai-Hock
Review in green synthesis mechanisms, application, and future prospects for Garcinia mangostana L. (mangosteen)-derived nanoparticles
Nanotechnology Reviews
green synthesis
nanomaterials
plant extracts
garcinia mangostana l.
phytochemicals
title Review in green synthesis mechanisms, application, and future prospects for Garcinia mangostana L. (mangosteen)-derived nanoparticles
title_full Review in green synthesis mechanisms, application, and future prospects for Garcinia mangostana L. (mangosteen)-derived nanoparticles
title_fullStr Review in green synthesis mechanisms, application, and future prospects for Garcinia mangostana L. (mangosteen)-derived nanoparticles
title_full_unstemmed Review in green synthesis mechanisms, application, and future prospects for Garcinia mangostana L. (mangosteen)-derived nanoparticles
title_short Review in green synthesis mechanisms, application, and future prospects for Garcinia mangostana L. (mangosteen)-derived nanoparticles
title_sort review in green synthesis mechanisms application and future prospects for garcinia mangostana l mangosteen derived nanoparticles
topic green synthesis
nanomaterials
plant extracts
garcinia mangostana l.
phytochemicals
url https://doi.org/10.1515/ntrev-2025-0157
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