IL-21 Expands HIV-1-Specific CD8+ T Memory Stem Cells to Suppress HIV-1 Replication In Vitro

IL-21 Expands HIV-1-Specific CD8+ T Memory Stem Cells to Suppress HIV-1 Replication In Vitro

Due to the existence of viral reservoirs, the rebound of human immunodeficiency virus type 1 (HIV-1) viremia can occur within weeks after discontinuing combined antiretroviral therapy. Immunotherapy could potentially be applied to eradicate reactivated HIV-1 in latently infected CD4+ T lymphocytes....

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Main Authors: Kang Wu, Shaoying Zhang, Xu Zhang, Xinghua Li, Zhongsi Hong, Fei Yu, Bingfeng Liu, Ting Pan, Zhaofeng Huang, Xiao-ping Tang, Weiping Cai, Jinyu Xia, Xuefeng Li, Hui Zhang, Yiwen Zhang, Linghua Li
Format: Article
Language:English
Published: Wiley 2019-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2019/1801560
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