Bronchiolitis Obliterans Organizing Pneumonia as an Initial Presentation of Systemic Lupus Erythematosus: A Rare Case Report and Literature Review

The etiology of bronchiolitis obliterans organizing pneumonia (BOOP) remains controversial. While it has been reportedly associated with several connective tissue disorders, there are only rare reports of BOOP associated with systemic lupus erythematosus (SLE). Herein, we report a 56-year-old female...

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Main Authors: Hung-Ping Wang, Chun-Ming Chen, Yih-Yuan Chen, Wei Chen
Format: Article
Language:English
Published: Wiley 2016-01-01
Series:Case Reports in Medicine
Online Access:http://dx.doi.org/10.1155/2016/8431741
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author Hung-Ping Wang
Chun-Ming Chen
Yih-Yuan Chen
Wei Chen
author_facet Hung-Ping Wang
Chun-Ming Chen
Yih-Yuan Chen
Wei Chen
author_sort Hung-Ping Wang
collection DOAJ
description The etiology of bronchiolitis obliterans organizing pneumonia (BOOP) remains controversial. While it has been reportedly associated with several connective tissue disorders, there are only rare reports of BOOP associated with systemic lupus erythematosus (SLE). Herein, we report a 56-year-old female patient who presented with dyspnea on exertion, cough, fever, and joint pain of her left wrist and fingers as initial symptoms. Laboratory tests revealed positivity for anti-nuclear antibody, anti-Ro, and anti-double strand DNA antibody. In this case, the patient with SLE had respiratory illness as the initial symptom due to BOOP in the absence of clear etiology. The diagnosis of BOOP was confirmed by thoracic surgery biopsy. Her respiratory symptoms and radiologic findings significantly improved following prednisolone treatment.
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spelling doaj-art-66a2d0f4336d44f9989099d4a2467cc02025-08-20T02:23:41ZengWileyCase Reports in Medicine1687-96271687-96352016-01-01201610.1155/2016/84317418431741Bronchiolitis Obliterans Organizing Pneumonia as an Initial Presentation of Systemic Lupus Erythematosus: A Rare Case Report and Literature ReviewHung-Ping Wang0Chun-Ming Chen1Yih-Yuan Chen2Wei Chen3Division of Allergy, Immunology and Rheumatology, Chiayi Christian Hospital, Chiayi 60002, TaiwanDivision of Allergy, Immunology and Rheumatology, Chiayi Christian Hospital, Chiayi 60002, TaiwanDepartment of Internal Medicine, Ditmanson Medical Foundation Chiayi Christian Hospital, Chiayi 60002, TaiwanDivision of Pulmonary and Critical Care Medicine, Ditmanson Medical Foundation Chiayi Christian Hospital, Chiayi 60002, TaiwanThe etiology of bronchiolitis obliterans organizing pneumonia (BOOP) remains controversial. While it has been reportedly associated with several connective tissue disorders, there are only rare reports of BOOP associated with systemic lupus erythematosus (SLE). Herein, we report a 56-year-old female patient who presented with dyspnea on exertion, cough, fever, and joint pain of her left wrist and fingers as initial symptoms. Laboratory tests revealed positivity for anti-nuclear antibody, anti-Ro, and anti-double strand DNA antibody. In this case, the patient with SLE had respiratory illness as the initial symptom due to BOOP in the absence of clear etiology. The diagnosis of BOOP was confirmed by thoracic surgery biopsy. Her respiratory symptoms and radiologic findings significantly improved following prednisolone treatment.http://dx.doi.org/10.1155/2016/8431741
spellingShingle Hung-Ping Wang
Chun-Ming Chen
Yih-Yuan Chen
Wei Chen
Bronchiolitis Obliterans Organizing Pneumonia as an Initial Presentation of Systemic Lupus Erythematosus: A Rare Case Report and Literature Review
Case Reports in Medicine
title Bronchiolitis Obliterans Organizing Pneumonia as an Initial Presentation of Systemic Lupus Erythematosus: A Rare Case Report and Literature Review
title_full Bronchiolitis Obliterans Organizing Pneumonia as an Initial Presentation of Systemic Lupus Erythematosus: A Rare Case Report and Literature Review
title_fullStr Bronchiolitis Obliterans Organizing Pneumonia as an Initial Presentation of Systemic Lupus Erythematosus: A Rare Case Report and Literature Review
title_full_unstemmed Bronchiolitis Obliterans Organizing Pneumonia as an Initial Presentation of Systemic Lupus Erythematosus: A Rare Case Report and Literature Review
title_short Bronchiolitis Obliterans Organizing Pneumonia as an Initial Presentation of Systemic Lupus Erythematosus: A Rare Case Report and Literature Review
title_sort bronchiolitis obliterans organizing pneumonia as an initial presentation of systemic lupus erythematosus a rare case report and literature review
url http://dx.doi.org/10.1155/2016/8431741
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