Effect of a polyherbal immunomodulator on the immunogenicity of booster dose of FMD and FMD-HS-BQ vaccines in dairy cattle

A polyherbal immunomodulator (restobal) was fed orally in dairy cattle (treatment group) to study its effect on the immunogenicity of booster dose of FMD and FMD-HS-BQ vaccines. Serum antibody titres for all three FMD virus serotypes were protective (1.80 log10 to 2.40 log10) in treatment and contr...

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Main Authors: NIDHI MISHRA, RASHMI SINGH, RAJNEESH SIROHI, BHASKAR GANGULY, SHREYA GUPTA, AKHIL KUMAR GUPTA
Format: Article
Language:English
Published: Indian Council of Agricultural Research 2025-02-01
Series:Indian Journal of Animal Sciences
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Online Access:https://epubs.icar.org.in/index.php/IJAnS/article/view/151036
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author NIDHI MISHRA
RASHMI SINGH
RAJNEESH SIROHI
BHASKAR GANGULY
SHREYA GUPTA
AKHIL KUMAR GUPTA
author_facet NIDHI MISHRA
RASHMI SINGH
RAJNEESH SIROHI
BHASKAR GANGULY
SHREYA GUPTA
AKHIL KUMAR GUPTA
author_sort NIDHI MISHRA
collection DOAJ
description A polyherbal immunomodulator (restobal) was fed orally in dairy cattle (treatment group) to study its effect on the immunogenicity of booster dose of FMD and FMD-HS-BQ vaccines. Serum antibody titres for all three FMD virus serotypes were protective (1.80 log10 to 2.40 log10) in treatment and control groups of vaccinated animals till 90 days of vaccination. Antibody titre did not differ significantly in control and treatment groups. Antibody titres ranging from 1.74 log10 to 1.92 log10 were observed for P. multocida and animals were protected on 90 days of vaccination in both control and treatment groups. The Restobal treated group was no different than the control group in antibody response to FMDV and P. multocida. Antibody response for FMDV was similar with FMD vaccine and FMD-HS-BQ vaccine.
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institution DOAJ
issn 0367-8318
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language English
publishDate 2025-02-01
publisher Indian Council of Agricultural Research
record_format Article
series Indian Journal of Animal Sciences
spelling doaj-art-669cbd3dd18a4d9e8fdf985b334dfa972025-08-20T03:23:37ZengIndian Council of Agricultural ResearchIndian Journal of Animal Sciences0367-83182394-33272025-02-0195210.56093/ijans.v95i2.151036Effect of a polyherbal immunomodulator on the immunogenicity of booster dose of FMD and FMD-HS-BQ vaccines in dairy cattleNIDHI MISHRA0RASHMI SINGH1RAJNEESH SIROHI2BHASKAR GANGULY3SHREYA GUPTA4AKHIL KUMAR GUPTA5U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura – 281001 (UP)U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura – 281001 (UP)U.P. Pandit Deen Dayal Upadhyaya Pashu Chikitsa Vigyan Vishwavidyalaya Evam Go-Anusandhan Sansthan (DUVASU), Mathura – 281001 (UP)Zenex Animal Health India Private Ltd.Zenex Animal Health India Private Ltd.Lala Lajpat Rai University of Veterinary and Animal Sciences (LUVAS), Hisar A polyherbal immunomodulator (restobal) was fed orally in dairy cattle (treatment group) to study its effect on the immunogenicity of booster dose of FMD and FMD-HS-BQ vaccines. Serum antibody titres for all three FMD virus serotypes were protective (1.80 log10 to 2.40 log10) in treatment and control groups of vaccinated animals till 90 days of vaccination. Antibody titre did not differ significantly in control and treatment groups. Antibody titres ranging from 1.74 log10 to 1.92 log10 were observed for P. multocida and animals were protected on 90 days of vaccination in both control and treatment groups. The Restobal treated group was no different than the control group in antibody response to FMDV and P. multocida. Antibody response for FMDV was similar with FMD vaccine and FMD-HS-BQ vaccine. https://epubs.icar.org.in/index.php/IJAnS/article/view/151036Cattle, Combined vaccine, Dairy, FMD, HS, Monovac, Polyherbal immunomodulator
spellingShingle NIDHI MISHRA
RASHMI SINGH
RAJNEESH SIROHI
BHASKAR GANGULY
SHREYA GUPTA
AKHIL KUMAR GUPTA
Effect of a polyherbal immunomodulator on the immunogenicity of booster dose of FMD and FMD-HS-BQ vaccines in dairy cattle
Indian Journal of Animal Sciences
Cattle, Combined vaccine, Dairy, FMD, HS, Monovac, Polyherbal immunomodulator
title Effect of a polyherbal immunomodulator on the immunogenicity of booster dose of FMD and FMD-HS-BQ vaccines in dairy cattle
title_full Effect of a polyherbal immunomodulator on the immunogenicity of booster dose of FMD and FMD-HS-BQ vaccines in dairy cattle
title_fullStr Effect of a polyherbal immunomodulator on the immunogenicity of booster dose of FMD and FMD-HS-BQ vaccines in dairy cattle
title_full_unstemmed Effect of a polyherbal immunomodulator on the immunogenicity of booster dose of FMD and FMD-HS-BQ vaccines in dairy cattle
title_short Effect of a polyherbal immunomodulator on the immunogenicity of booster dose of FMD and FMD-HS-BQ vaccines in dairy cattle
title_sort effect of a polyherbal immunomodulator on the immunogenicity of booster dose of fmd and fmd hs bq vaccines in dairy cattle
topic Cattle, Combined vaccine, Dairy, FMD, HS, Monovac, Polyherbal immunomodulator
url https://epubs.icar.org.in/index.php/IJAnS/article/view/151036
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