Catheter-Related Acremonium kiliense Fungemia in a Patient with Ulcerative Colitis under Treatment with Infliximab

Acremonium spp. are filamentous, cosmopolitan fungi commonly isolated from plant debris and soil. They are infrequent pathogens in humans. Acremonium fungemia has been reported in neutropenic patients associated with central venous catheters and in nonneutropenic patients receiving long-term total p...

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Main Authors: Fernando A. Díaz-Couselo, Marcelo Zylberman
Format: Article
Language:English
Published: Wiley 2011-01-01
Series:Case Reports in Infectious Diseases
Online Access:http://dx.doi.org/10.1155/2011/710740
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author Fernando A. Díaz-Couselo
Marcelo Zylberman
author_facet Fernando A. Díaz-Couselo
Marcelo Zylberman
author_sort Fernando A. Díaz-Couselo
collection DOAJ
description Acremonium spp. are filamentous, cosmopolitan fungi commonly isolated from plant debris and soil. They are infrequent pathogens in humans. Acremonium fungemia has been reported in neutropenic patients associated with central venous catheters and in nonneutropenic patients receiving long-term total parenteral nutrition. TNF-α blockade is associated with fungal infections, but no Acremonium spp. infection had been reported up to the present. In this paper, we present a patient with ulcerative colitis who developed Acremonium kiliense fungemia associated with infliximab therapy while receiving total parenteral nutrition. The patient was successfully treated with voriconazole. Acremonium sp. infection must be suspected as another cause of fungal infection in patients under treatment with infliximab.
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series Case Reports in Infectious Diseases
spelling doaj-art-6699a22a53c14ce29754fa7a048787322025-02-03T05:48:26ZengWileyCase Reports in Infectious Diseases2090-66252090-66332011-01-01201110.1155/2011/710740710740Catheter-Related Acremonium kiliense Fungemia in a Patient with Ulcerative Colitis under Treatment with InfliximabFernando A. Díaz-Couselo0Marcelo Zylberman1Instituto Alexander Fleming, Crámer 1180. Ciudad Autónoma de Buenos Aires, C1426ANZ, ArgentinaInstituto Alexander Fleming, Crámer 1180. Ciudad Autónoma de Buenos Aires, C1426ANZ, ArgentinaAcremonium spp. are filamentous, cosmopolitan fungi commonly isolated from plant debris and soil. They are infrequent pathogens in humans. Acremonium fungemia has been reported in neutropenic patients associated with central venous catheters and in nonneutropenic patients receiving long-term total parenteral nutrition. TNF-α blockade is associated with fungal infections, but no Acremonium spp. infection had been reported up to the present. In this paper, we present a patient with ulcerative colitis who developed Acremonium kiliense fungemia associated with infliximab therapy while receiving total parenteral nutrition. The patient was successfully treated with voriconazole. Acremonium sp. infection must be suspected as another cause of fungal infection in patients under treatment with infliximab.http://dx.doi.org/10.1155/2011/710740
spellingShingle Fernando A. Díaz-Couselo
Marcelo Zylberman
Catheter-Related Acremonium kiliense Fungemia in a Patient with Ulcerative Colitis under Treatment with Infliximab
Case Reports in Infectious Diseases
title Catheter-Related Acremonium kiliense Fungemia in a Patient with Ulcerative Colitis under Treatment with Infliximab
title_full Catheter-Related Acremonium kiliense Fungemia in a Patient with Ulcerative Colitis under Treatment with Infliximab
title_fullStr Catheter-Related Acremonium kiliense Fungemia in a Patient with Ulcerative Colitis under Treatment with Infliximab
title_full_unstemmed Catheter-Related Acremonium kiliense Fungemia in a Patient with Ulcerative Colitis under Treatment with Infliximab
title_short Catheter-Related Acremonium kiliense Fungemia in a Patient with Ulcerative Colitis under Treatment with Infliximab
title_sort catheter related acremonium kiliense fungemia in a patient with ulcerative colitis under treatment with infliximab
url http://dx.doi.org/10.1155/2011/710740
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AT marcelozylberman catheterrelatedacremoniumkiliensefungemiainapatientwithulcerativecolitisundertreatmentwithinfliximab