Electrospun short fibers: a new platform for cancer nanomedicine applications
With the continuous development of nanomaterials, nanofibers prepared by electrospinning have gradually occupied people’s vision because of their unique advantages, such as crisscross network and extracellular matrix-mimicking structure, high drug loading efficiency, and sustained release kinetics....
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| Format: | Article |
| Language: | English |
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Open Exploration
2023-12-01
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| Series: | Exploration of Drug Science |
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| Online Access: | https://www.explorationpub.com/uploads/Article/A100830/100830.pdf |
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| _version_ | 1825199573494136832 |
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| author | Yifan Huang Mengsi Zhan Mingwu Shen Lili Zhang Xiangyang Shi |
| author_facet | Yifan Huang Mengsi Zhan Mingwu Shen Lili Zhang Xiangyang Shi |
| author_sort | Yifan Huang |
| collection | DOAJ |
| description | With the continuous development of nanomaterials, nanofibers prepared by electrospinning have gradually occupied people’s vision because of their unique advantages, such as crisscross network and extracellular matrix-mimicking structure, high drug loading efficiency, and sustained release kinetics. Traditionally, electrospun fibers are mainly used as filter materials, wound dressings, and tissue engineering scaffolds, while their wide applications are limited to cancer nanomedicine applications due to their dense network structure. In recent years, two-dimensional fiber membranes have been transformed into short fibers that can be reconstructed to form fibrous rings or microspheres for cancer theranostics. Herein, this paper provides an overview of the recent advances in the design of electrospun short fibers that retain the advantages of nanofibers with good dispersibility for different nanomedicine applications, including cancer cell capture, cancer treatments, and cancer theranostics. The rational preparation of electrospun short fibers that are available to boost the development of nanomedicine is also discussed. |
| format | Article |
| id | doaj-art-667e76d97f2c4665ae1e0e5d61389fee |
| institution | Kabale University |
| issn | 2836-7677 |
| language | English |
| publishDate | 2023-12-01 |
| publisher | Open Exploration |
| record_format | Article |
| series | Exploration of Drug Science |
| spelling | doaj-art-667e76d97f2c4665ae1e0e5d61389fee2025-02-08T03:44:56ZengOpen ExplorationExploration of Drug Science2836-76772023-12-011645446710.37349/eds.2023.00030Electrospun short fibers: a new platform for cancer nanomedicine applicationsYifan Huang0https://orcid.org/0009-0007-8555-318XMengsi Zhan1Mingwu Shen2https://orcid.org/0000-0002-1065-0854Lili Zhang3Xiangyang Shi4https://orcid.org/0000-0001-6785-6645State Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, ChinaState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, ChinaState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, ChinaNanyang Ecological Environment Monitoring and Safety Center, Nanyang 473000, Henan, ChinaState Key Laboratory for Modification of Chemical Fibers and Polymer Materials, Shanghai Engineering Research Center of Nano-Biomaterials and Regenerative Medicine, College of Biological Science and Medical Engineering, Donghua University, Shanghai 201620, China; CQM-Centro de Química da Madeira, Universidade da Madeira, 9020-105 Funchal, PortugalWith the continuous development of nanomaterials, nanofibers prepared by electrospinning have gradually occupied people’s vision because of their unique advantages, such as crisscross network and extracellular matrix-mimicking structure, high drug loading efficiency, and sustained release kinetics. Traditionally, electrospun fibers are mainly used as filter materials, wound dressings, and tissue engineering scaffolds, while their wide applications are limited to cancer nanomedicine applications due to their dense network structure. In recent years, two-dimensional fiber membranes have been transformed into short fibers that can be reconstructed to form fibrous rings or microspheres for cancer theranostics. Herein, this paper provides an overview of the recent advances in the design of electrospun short fibers that retain the advantages of nanofibers with good dispersibility for different nanomedicine applications, including cancer cell capture, cancer treatments, and cancer theranostics. The rational preparation of electrospun short fibers that are available to boost the development of nanomedicine is also discussed.https://www.explorationpub.com/uploads/Article/A100830/100830.pdfelectrospinningshort fibersdrug deliverycancer treatmentscancer theranostics |
| spellingShingle | Yifan Huang Mengsi Zhan Mingwu Shen Lili Zhang Xiangyang Shi Electrospun short fibers: a new platform for cancer nanomedicine applications Exploration of Drug Science electrospinning short fibers drug delivery cancer treatments cancer theranostics |
| title | Electrospun short fibers: a new platform for cancer nanomedicine applications |
| title_full | Electrospun short fibers: a new platform for cancer nanomedicine applications |
| title_fullStr | Electrospun short fibers: a new platform for cancer nanomedicine applications |
| title_full_unstemmed | Electrospun short fibers: a new platform for cancer nanomedicine applications |
| title_short | Electrospun short fibers: a new platform for cancer nanomedicine applications |
| title_sort | electrospun short fibers a new platform for cancer nanomedicine applications |
| topic | electrospinning short fibers drug delivery cancer treatments cancer theranostics |
| url | https://www.explorationpub.com/uploads/Article/A100830/100830.pdf |
| work_keys_str_mv | AT yifanhuang electrospunshortfibersanewplatformforcancernanomedicineapplications AT mengsizhan electrospunshortfibersanewplatformforcancernanomedicineapplications AT mingwushen electrospunshortfibersanewplatformforcancernanomedicineapplications AT lilizhang electrospunshortfibersanewplatformforcancernanomedicineapplications AT xiangyangshi electrospunshortfibersanewplatformforcancernanomedicineapplications |