Factors contributing to mosquito-borne disease: A systematic review in the Middle East and North Africa (MENA) region

Mosquitoes can carry and spread many diseases caused by bacteria, viruses, or parasites. All these mosquito-borne diseases (MBD) represent a significant global burden of infectious diseases, including morbidity and mortality. This systematic review delves into the multifaceted factors contributing t...

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Main Authors: Abdullah Al-Manji, Anak Agung Bagus Wirayuda, Rawaa Abubakr Abuelgassim Eltayib, Mohammed Al-Azri, Moon Fai Chan
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Current Research in Parasitology and Vector-Borne Diseases
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Online Access:http://www.sciencedirect.com/science/article/pii/S2667114X2500041X
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author Abdullah Al-Manji
Anak Agung Bagus Wirayuda
Rawaa Abubakr Abuelgassim Eltayib
Mohammed Al-Azri
Moon Fai Chan
author_facet Abdullah Al-Manji
Anak Agung Bagus Wirayuda
Rawaa Abubakr Abuelgassim Eltayib
Mohammed Al-Azri
Moon Fai Chan
author_sort Abdullah Al-Manji
collection DOAJ
description Mosquitoes can carry and spread many diseases caused by bacteria, viruses, or parasites. All these mosquito-borne diseases (MBD) represent a significant global burden of infectious diseases, including morbidity and mortality. This systematic review delves into the multifaceted factors contributing to the spread of MBD in the Middle East and North Africa (MENA) region. Following PRISMA guidelines, we reviewed peer-reviewed English-language observational and experimental studies published between May 1990 and January 2023, focusing on the interaction between population, environmental, disease, and mosquito factors in MBD. The review includes 32 studies (30 articles) that revealed a complex relationship between various risk factors and the presence of MBD. The review distinguishes between seroprevalence studies, which assess exposure to infection in asymptomatic populations, and overt disease studies, which focus on symptomatic cases and the host-specific factors that affect disease severity. It identifies key risk factors such as age, geography, gender, professional occupation, and socio-economic status, noting their varying impacts on disease transmission and progression across different MBDs. Environmental factors such as climate, mosquito breeding habitats, and urbanization are also reported as significant drivers of vector distribution and human-vector interactions. The review emphasizes the need for tailored, region-specific interventions to control MBD in the MENA region and highlights the importance of integrated vector control, improved sanitation, surveillance programmes, and public health education. The review also stresses the growing influence of climate change on disease patterns and calls for a multi-sectoral approach to MBD control. While focusing on the MENA region, the findings suggest the need for further research and region-specific public health policies to mitigate the impact of these diseases.
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spelling doaj-art-666fb7e0096a41a49f9fb01ed80061e82025-08-20T03:30:41ZengElsevierCurrent Research in Parasitology and Vector-Borne Diseases2667-114X2025-01-01810028110.1016/j.crpvbd.2025.100281Factors contributing to mosquito-borne disease: A systematic review in the Middle East and North Africa (MENA) regionAbdullah Al-Manji0Anak Agung Bagus Wirayuda1Rawaa Abubakr Abuelgassim Eltayib2Mohammed Al-Azri3Moon Fai Chan4Department of Family Medicine and Public Health, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, OmanDepartment of Family Medicine and Public Health, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman; Faculty of Medicine and Health, Institut Teknologi Sepuluh Nopember, Surabaya, IndonesiaDepartment of Family Medicine and Public Health, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, OmanDepartment of Family Medicine and Public Health, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, OmanDepartment of Family Medicine and Public Health, College of Medicine and Health Sciences, Sultan Qaboos University, Muscat, Oman; Corresponding author.Mosquitoes can carry and spread many diseases caused by bacteria, viruses, or parasites. All these mosquito-borne diseases (MBD) represent a significant global burden of infectious diseases, including morbidity and mortality. This systematic review delves into the multifaceted factors contributing to the spread of MBD in the Middle East and North Africa (MENA) region. Following PRISMA guidelines, we reviewed peer-reviewed English-language observational and experimental studies published between May 1990 and January 2023, focusing on the interaction between population, environmental, disease, and mosquito factors in MBD. The review includes 32 studies (30 articles) that revealed a complex relationship between various risk factors and the presence of MBD. The review distinguishes between seroprevalence studies, which assess exposure to infection in asymptomatic populations, and overt disease studies, which focus on symptomatic cases and the host-specific factors that affect disease severity. It identifies key risk factors such as age, geography, gender, professional occupation, and socio-economic status, noting their varying impacts on disease transmission and progression across different MBDs. Environmental factors such as climate, mosquito breeding habitats, and urbanization are also reported as significant drivers of vector distribution and human-vector interactions. The review emphasizes the need for tailored, region-specific interventions to control MBD in the MENA region and highlights the importance of integrated vector control, improved sanitation, surveillance programmes, and public health education. The review also stresses the growing influence of climate change on disease patterns and calls for a multi-sectoral approach to MBD control. While focusing on the MENA region, the findings suggest the need for further research and region-specific public health policies to mitigate the impact of these diseases.http://www.sciencedirect.com/science/article/pii/S2667114X2500041XMENA regionMosquito-borne diseaseDengueMalariaChikungunyaWest Nile fever
spellingShingle Abdullah Al-Manji
Anak Agung Bagus Wirayuda
Rawaa Abubakr Abuelgassim Eltayib
Mohammed Al-Azri
Moon Fai Chan
Factors contributing to mosquito-borne disease: A systematic review in the Middle East and North Africa (MENA) region
Current Research in Parasitology and Vector-Borne Diseases
MENA region
Mosquito-borne disease
Dengue
Malaria
Chikungunya
West Nile fever
title Factors contributing to mosquito-borne disease: A systematic review in the Middle East and North Africa (MENA) region
title_full Factors contributing to mosquito-borne disease: A systematic review in the Middle East and North Africa (MENA) region
title_fullStr Factors contributing to mosquito-borne disease: A systematic review in the Middle East and North Africa (MENA) region
title_full_unstemmed Factors contributing to mosquito-borne disease: A systematic review in the Middle East and North Africa (MENA) region
title_short Factors contributing to mosquito-borne disease: A systematic review in the Middle East and North Africa (MENA) region
title_sort factors contributing to mosquito borne disease a systematic review in the middle east and north africa mena region
topic MENA region
Mosquito-borne disease
Dengue
Malaria
Chikungunya
West Nile fever
url http://www.sciencedirect.com/science/article/pii/S2667114X2500041X
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