Microbiome sharing between children, livestock and household surfaces in western Kenya.
The gut microbiome community structure and development are associated with several health outcomes in young children. To determine the household influences of gut microbiome structure, we assessed microbial sharing within households in western Kenya by sequencing 16S rRNA libraries of fecal samples...
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| Format: | Article |
| Language: | English |
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Public Library of Science (PLoS)
2017-01-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171017&type=printable |
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| author | Emily Mosites Matt Sammons Elkanah Otiang Alexander Eng Cecilia Noecker Ohad Manor Sarah Hilton Samuel M Thumbi Clayton Onyango Gemina Garland-Lewis Douglas R Call M Kariuki Njenga Judith N Wasserheit Jennifer A Zambriski Judd L Walson Guy H Palmer Joel Montgomery Elhanan Borenstein Richard Omore Peter M Rabinowitz |
| author_facet | Emily Mosites Matt Sammons Elkanah Otiang Alexander Eng Cecilia Noecker Ohad Manor Sarah Hilton Samuel M Thumbi Clayton Onyango Gemina Garland-Lewis Douglas R Call M Kariuki Njenga Judith N Wasserheit Jennifer A Zambriski Judd L Walson Guy H Palmer Joel Montgomery Elhanan Borenstein Richard Omore Peter M Rabinowitz |
| author_sort | Emily Mosites |
| collection | DOAJ |
| description | The gut microbiome community structure and development are associated with several health outcomes in young children. To determine the household influences of gut microbiome structure, we assessed microbial sharing within households in western Kenya by sequencing 16S rRNA libraries of fecal samples from children and cattle, cloacal swabs from chickens, and swabs of household surfaces. Among the 156 households studied, children within the same household significantly shared their gut microbiome with each other, although we did not find significant sharing of gut microbiome across host species or household surfaces. Higher gut microbiome diversity among children was associated with lower wealth status and involvement in livestock feeding chores. Although more research is necessary to identify further drivers of microbiota development, these results suggest that the household should be considered as a unit. Livestock activities, health and microbiome perturbations among an individual child may have implications for other children in the household. |
| format | Article |
| id | doaj-art-6667bb1d4f0841b59bdb441797627f69 |
| institution | OA Journals |
| issn | 1932-6203 |
| language | English |
| publishDate | 2017-01-01 |
| publisher | Public Library of Science (PLoS) |
| record_format | Article |
| series | PLoS ONE |
| spelling | doaj-art-6667bb1d4f0841b59bdb441797627f692025-08-20T02:03:54ZengPublic Library of Science (PLoS)PLoS ONE1932-62032017-01-01122e017101710.1371/journal.pone.0171017Microbiome sharing between children, livestock and household surfaces in western Kenya.Emily MositesMatt SammonsElkanah OtiangAlexander EngCecilia NoeckerOhad ManorSarah HiltonSamuel M ThumbiClayton OnyangoGemina Garland-LewisDouglas R CallM Kariuki NjengaJudith N WasserheitJennifer A ZambriskiJudd L WalsonGuy H PalmerJoel MontgomeryElhanan BorensteinRichard OmorePeter M RabinowitzThe gut microbiome community structure and development are associated with several health outcomes in young children. To determine the household influences of gut microbiome structure, we assessed microbial sharing within households in western Kenya by sequencing 16S rRNA libraries of fecal samples from children and cattle, cloacal swabs from chickens, and swabs of household surfaces. Among the 156 households studied, children within the same household significantly shared their gut microbiome with each other, although we did not find significant sharing of gut microbiome across host species or household surfaces. Higher gut microbiome diversity among children was associated with lower wealth status and involvement in livestock feeding chores. Although more research is necessary to identify further drivers of microbiota development, these results suggest that the household should be considered as a unit. Livestock activities, health and microbiome perturbations among an individual child may have implications for other children in the household.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171017&type=printable |
| spellingShingle | Emily Mosites Matt Sammons Elkanah Otiang Alexander Eng Cecilia Noecker Ohad Manor Sarah Hilton Samuel M Thumbi Clayton Onyango Gemina Garland-Lewis Douglas R Call M Kariuki Njenga Judith N Wasserheit Jennifer A Zambriski Judd L Walson Guy H Palmer Joel Montgomery Elhanan Borenstein Richard Omore Peter M Rabinowitz Microbiome sharing between children, livestock and household surfaces in western Kenya. PLoS ONE |
| title | Microbiome sharing between children, livestock and household surfaces in western Kenya. |
| title_full | Microbiome sharing between children, livestock and household surfaces in western Kenya. |
| title_fullStr | Microbiome sharing between children, livestock and household surfaces in western Kenya. |
| title_full_unstemmed | Microbiome sharing between children, livestock and household surfaces in western Kenya. |
| title_short | Microbiome sharing between children, livestock and household surfaces in western Kenya. |
| title_sort | microbiome sharing between children livestock and household surfaces in western kenya |
| url | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0171017&type=printable |
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