Natural microbial exposure populates the maternal fetal interface with diverse T cells

Natural microbial exposure populates the maternal fetal interface with diverse T cells

Diverse T cell types accumulate at the human maternal fetal interface (MFI) during pregnancy to orchestrate immune tolerance for foreign fetal/placental tissues and immunity to pathogens. Yet, the dynamics of T cell influx and function at the MFI remain poorly defined. Conventional specific pathogen...

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Bibliographic Details
Main Authors: Amy Whillock, Perianne Smith, Sarah Burger, Adhvaith Sridhar, Alex Lindgren, James Berg, Sayaka Tsuda, Shweta Mahajan, Tamara Tilburgs, Nathaniel J. Schuldt
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-07-01
Series:Frontiers in Immunology
Subjects:
pregnancy
T cells
maternal fetal interface
dirty mice
microbial exposure
placenta
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1616491/full
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