Time to consider doxycycline in the standard treatment of lymphatic filariasis? Emerging evidence on use of doxycycline as an adjunct to hygiene protocols
Abstract With lymphatic filariasis being a rampant condition in tropical countries, multiple treatment modalities are being explored for their efficacy and practicability of use in low resource settings. Doxycycline, a commonly available drug across the world, has been proposed to improve patient st...
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| Format: | Article |
| Language: | English |
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BMC
2025-03-01
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| Series: | Tropical Medicine and Health |
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| Online Access: | https://doi.org/10.1186/s41182-025-00726-4 |
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| author | Mian Zahid Jan Kakakhel Shree Rath Maheen Sheraz Diya Rathi Raheel Ahmed |
| author_facet | Mian Zahid Jan Kakakhel Shree Rath Maheen Sheraz Diya Rathi Raheel Ahmed |
| author_sort | Mian Zahid Jan Kakakhel |
| collection | DOAJ |
| description | Abstract With lymphatic filariasis being a rampant condition in tropical countries, multiple treatment modalities are being explored for their efficacy and practicability of use in low resource settings. Doxycycline, a commonly available drug across the world, has been proposed to improve patient status in those suffering with lymphatic filariasis. In conjunct with hygiene protocols, emerging trials have highlighted the success of doxycycline as an add-on drug. In this letter, we highlight the major findings in recent trials, and the scope of integrating doxycycline into national elimination strategies against filariasis. |
| format | Article |
| id | doaj-art-6659b1b24a0645fcbdcd654d4134ab3b |
| institution | OA Journals |
| issn | 1349-4147 |
| language | English |
| publishDate | 2025-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Tropical Medicine and Health |
| spelling | doaj-art-6659b1b24a0645fcbdcd654d4134ab3b2025-08-20T02:10:23ZengBMCTropical Medicine and Health1349-41472025-03-015311310.1186/s41182-025-00726-4Time to consider doxycycline in the standard treatment of lymphatic filariasis? Emerging evidence on use of doxycycline as an adjunct to hygiene protocolsMian Zahid Jan Kakakhel0Shree Rath1Maheen Sheraz2Diya Rathi3Raheel Ahmed4Rehman Medical CollegeAll India Institute of Medical SciencesContinental Medical CollegeDow University of Health SciencesNational Heart and Lung Institute, Imperial College LondonAbstract With lymphatic filariasis being a rampant condition in tropical countries, multiple treatment modalities are being explored for their efficacy and practicability of use in low resource settings. Doxycycline, a commonly available drug across the world, has been proposed to improve patient status in those suffering with lymphatic filariasis. In conjunct with hygiene protocols, emerging trials have highlighted the success of doxycycline as an add-on drug. In this letter, we highlight the major findings in recent trials, and the scope of integrating doxycycline into national elimination strategies against filariasis.https://doi.org/10.1186/s41182-025-00726-4DoxycyclineLymphatic filariasisHygiene protocols |
| spellingShingle | Mian Zahid Jan Kakakhel Shree Rath Maheen Sheraz Diya Rathi Raheel Ahmed Time to consider doxycycline in the standard treatment of lymphatic filariasis? Emerging evidence on use of doxycycline as an adjunct to hygiene protocols Tropical Medicine and Health Doxycycline Lymphatic filariasis Hygiene protocols |
| title | Time to consider doxycycline in the standard treatment of lymphatic filariasis? Emerging evidence on use of doxycycline as an adjunct to hygiene protocols |
| title_full | Time to consider doxycycline in the standard treatment of lymphatic filariasis? Emerging evidence on use of doxycycline as an adjunct to hygiene protocols |
| title_fullStr | Time to consider doxycycline in the standard treatment of lymphatic filariasis? Emerging evidence on use of doxycycline as an adjunct to hygiene protocols |
| title_full_unstemmed | Time to consider doxycycline in the standard treatment of lymphatic filariasis? Emerging evidence on use of doxycycline as an adjunct to hygiene protocols |
| title_short | Time to consider doxycycline in the standard treatment of lymphatic filariasis? Emerging evidence on use of doxycycline as an adjunct to hygiene protocols |
| title_sort | time to consider doxycycline in the standard treatment of lymphatic filariasis emerging evidence on use of doxycycline as an adjunct to hygiene protocols |
| topic | Doxycycline Lymphatic filariasis Hygiene protocols |
| url | https://doi.org/10.1186/s41182-025-00726-4 |
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