Diagnosis of Good Syndrome following Recurrent Coronavirus Disease-2019 Infections
Background: Good syndrome is defined as the co-occurrence of a thymoma and hypogammaglobulinemia. Case: In this case report, we present a patient who was diagnosed with Good syndrome following recurrent infections with SARS-CoV-2. Of particular note was the patient’s repeated pre...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
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Karger Publishers
2025-01-01
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| Series: | Case Reports in Oncology |
| Online Access: | https://karger.com/article/doi/10.1159/000542928 |
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| _version_ | 1849727622711345152 |
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| author | Moshe Beiser Joshua K. Sabari |
| author_facet | Moshe Beiser Joshua K. Sabari |
| author_sort | Moshe Beiser |
| collection | DOAJ |
| description |
Background:
Good syndrome is defined as the co-occurrence of a thymoma and hypogammaglobulinemia.
Case:
In this case report, we present a patient who was diagnosed with Good syndrome following recurrent infections with SARS-CoV-2. Of particular note was the patient’s repeated presentation despite receiving outpatient treatment with nirmatrelvir-ritonavir. We describe the patient’s presentation, diagnosis, and treatment – including robotic thymectomy and passive immunization with IVIG – and report the benefit to quality of life that the patient experienced.
Conclusion:
This case highlights the importance of quantitative testing of immunoglobulins in patients with known thymomas who present with recurrent infections of SARS-CoV-2.
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| format | Article |
| id | doaj-art-6647de07737e44d0aefbcd07263f5798 |
| institution | DOAJ |
| issn | 1662-6575 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | Karger Publishers |
| record_format | Article |
| series | Case Reports in Oncology |
| spelling | doaj-art-6647de07737e44d0aefbcd07263f57982025-08-20T03:09:48ZengKarger PublishersCase Reports in Oncology1662-65752025-01-0118110711210.1159/000542928Diagnosis of Good Syndrome following Recurrent Coronavirus Disease-2019 InfectionsMoshe BeiserJoshua K. Sabari Background: Good syndrome is defined as the co-occurrence of a thymoma and hypogammaglobulinemia. Case: In this case report, we present a patient who was diagnosed with Good syndrome following recurrent infections with SARS-CoV-2. Of particular note was the patient’s repeated presentation despite receiving outpatient treatment with nirmatrelvir-ritonavir. We describe the patient’s presentation, diagnosis, and treatment – including robotic thymectomy and passive immunization with IVIG – and report the benefit to quality of life that the patient experienced. Conclusion: This case highlights the importance of quantitative testing of immunoglobulins in patients with known thymomas who present with recurrent infections of SARS-CoV-2. https://karger.com/article/doi/10.1159/000542928 |
| spellingShingle | Moshe Beiser Joshua K. Sabari Diagnosis of Good Syndrome following Recurrent Coronavirus Disease-2019 Infections Case Reports in Oncology |
| title | Diagnosis of Good Syndrome following Recurrent Coronavirus Disease-2019 Infections |
| title_full | Diagnosis of Good Syndrome following Recurrent Coronavirus Disease-2019 Infections |
| title_fullStr | Diagnosis of Good Syndrome following Recurrent Coronavirus Disease-2019 Infections |
| title_full_unstemmed | Diagnosis of Good Syndrome following Recurrent Coronavirus Disease-2019 Infections |
| title_short | Diagnosis of Good Syndrome following Recurrent Coronavirus Disease-2019 Infections |
| title_sort | diagnosis of good syndrome following recurrent coronavirus disease 2019 infections |
| url | https://karger.com/article/doi/10.1159/000542928 |
| work_keys_str_mv | AT moshebeiser diagnosisofgoodsyndromefollowingrecurrentcoronavirusdisease2019infections AT joshuaksabari diagnosisofgoodsyndromefollowingrecurrentcoronavirusdisease2019infections |