Diagnosis of Good Syndrome following Recurrent Coronavirus Disease-2019 Infections

Background: Good syndrome is defined as the co-occurrence of a thymoma and hypogammaglobulinemia. Case: In this case report, we present a patient who was diagnosed with Good syndrome following recurrent infections with SARS-CoV-2. Of particular note was the patient’s repeated pre...

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Bibliographic Details
Main Authors: Moshe Beiser, Joshua K. Sabari
Format: Article
Language:English
Published: Karger Publishers 2025-01-01
Series:Case Reports in Oncology
Online Access:https://karger.com/article/doi/10.1159/000542928
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Summary:Background: Good syndrome is defined as the co-occurrence of a thymoma and hypogammaglobulinemia. Case: In this case report, we present a patient who was diagnosed with Good syndrome following recurrent infections with SARS-CoV-2. Of particular note was the patient’s repeated presentation despite receiving outpatient treatment with nirmatrelvir-ritonavir. We describe the patient’s presentation, diagnosis, and treatment – including robotic thymectomy and passive immunization with IVIG – and report the benefit to quality of life that the patient experienced. Conclusion: This case highlights the importance of quantitative testing of immunoglobulins in patients with known thymomas who present with recurrent infections of SARS-CoV-2.
ISSN:1662-6575