SOuLMuSiC, a novel tool for predicting the impact of mutations on protein solubility

Abstract Protein solubility problems arise in a wide range of applications, from antibody development to enzyme production, and are linked to several major disorders, including cataracts and Alzheimer’s diseases. To assist scientists in designing proteins with improved solubility and better understa...

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Bibliographic Details
Main Authors: Simone Attanasio, Jean Kwasigroch, Marianne Rooman, Fabrizio Pucci
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-11326-x
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