Overcoming leukemia heterogeneity by combining T cell engaging bispecific antibodies
Background Leukemia represents about 5% of all human cancers. Despite advances in therapeutics, a substantial number of patients succumb to the disease. Several subtypes of leukemia are inherently more resistant to treatment despite intensive chemotherapy or targeted therapy.Methods Here we describe...
Saved in:
| Main Authors: | Madelyn Espinosa-Cotton, Sayed Shahabuddin Hoseini, Hong-fen Guo, Nai-Kong V Cheung |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMJ Publishing Group
2020-10-01
|
| Series: | Journal for ImmunoTherapy of Cancer |
| Online Access: | https://jitc.bmj.com/content/8/2/e001626.full |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
Advances of bispecific antibodies using/application in dermatology: a review
by: Ting Zhang, et al.
Published: (2025-08-01) -
A roadmap to implementing outpatient administration of bispecific antibodies in multiple myeloma
by: Alfred L. Garfall, et al.
Published: (2025-07-01) -
Kinetic analysis of ternary and binary binding modes of the bispecific antibody emicizumab
by: Stefanie Mak, et al.
Published: (2023-12-01) -
The silent signals: emerging safety concerns in bispecific antibody therapy for multiple myeloma
by: Xiaoling Zhou, et al.
Published: (2025-08-01) -
Resistance Mechanisms to BCMA Targeting Bispecific Antibodies and CAR T-Cell Therapies in Multiple Myeloma
by: Brandon Tedder, et al.
Published: (2025-07-01)