Short-Term Inhibition of NOX2 Prevents the Development of Aβ-Induced Pathology in Mice
Alzheimer’s disease (AD) is the most common neurodegenerative disorder, characterized by the formation of neurotoxic beta-amyloid (Aβ) oligomers in the central nervous system. One of the earliest pathological effects of Aβ is the induction of oxidative stress in brain tissue, mediated by NADPH oxida...
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| Main Authors: | Kristina A. Mukhina, Olga I. Kechko, Alexander A. Osypov, Irina Yu. Petrushanko, Alexander A. Makarov, Vladimir A. Mitkevich, Irina Yu. Popova |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
MDPI AG
2025-05-01
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| Series: | Antioxidants |
| Subjects: | |
| Online Access: | https://www.mdpi.com/2076-3921/14/6/663 |
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