Identification of novel miRNAs and miRNA expression profiling in wheat hybrid necrosis.

MicroRNAs (miRNAs) play essential roles in a vast array of biological processes, including growth and development, defense against viral infection, and responses to environmental changes in plant. Wheat hybrid necrosis is an interesting genetic phenomenon observed frequency and it is lethal or semi...

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Main Authors: Jianping Zhou, Yan Cheng, Meiqi Yin, Ennian Yang, Wenping Gong, Cheng Liu, Xuelian Zheng, Kejun Deng, Zhenglong Ren, Yong Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117507&type=printable
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author Jianping Zhou
Yan Cheng
Meiqi Yin
Ennian Yang
Wenping Gong
Cheng Liu
Xuelian Zheng
Kejun Deng
Zhenglong Ren
Yong Zhang
author_facet Jianping Zhou
Yan Cheng
Meiqi Yin
Ennian Yang
Wenping Gong
Cheng Liu
Xuelian Zheng
Kejun Deng
Zhenglong Ren
Yong Zhang
author_sort Jianping Zhou
collection DOAJ
description MicroRNAs (miRNAs) play essential roles in a vast array of biological processes, including growth and development, defense against viral infection, and responses to environmental changes in plant. Wheat hybrid necrosis is an interesting genetic phenomenon observed frequency and it is lethal or semi lethal, resulting in gradual death or loss of productivity. However, the molecular basis and mechanisms associated with hybrid necrosis in wheat are still not well understood. Here, we report the population and expression profiles of miRNAs in wheat hybrid necrosis. We identified a total of 57 conserved miRNA families as well as 182 putative novel miRNAs. Expression profiling revealed that expression of 49 known miRNAs and 165 novel miRNAs was changed in hybrid necrosis. And the expression levels of some miRNAs and their predicated targets have been confirmed by qRT-PCR. These results indicate that these miRNAs, especially miR159, miR166, miR167 and miR5072 could be involved in the extensive regulation of gene expression in response to hybrid necrosis.
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institution OA Journals
issn 1932-6203
language English
publishDate 2015-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj-art-6629cd50c1e046c1a5efad7221cdcd832025-08-20T02:15:02ZengPublic Library of Science (PLoS)PLoS ONE1932-62032015-01-01102e011750710.1371/journal.pone.0117507Identification of novel miRNAs and miRNA expression profiling in wheat hybrid necrosis.Jianping ZhouYan ChengMeiqi YinEnnian YangWenping GongCheng LiuXuelian ZhengKejun DengZhenglong RenYong ZhangMicroRNAs (miRNAs) play essential roles in a vast array of biological processes, including growth and development, defense against viral infection, and responses to environmental changes in plant. Wheat hybrid necrosis is an interesting genetic phenomenon observed frequency and it is lethal or semi lethal, resulting in gradual death or loss of productivity. However, the molecular basis and mechanisms associated with hybrid necrosis in wheat are still not well understood. Here, we report the population and expression profiles of miRNAs in wheat hybrid necrosis. We identified a total of 57 conserved miRNA families as well as 182 putative novel miRNAs. Expression profiling revealed that expression of 49 known miRNAs and 165 novel miRNAs was changed in hybrid necrosis. And the expression levels of some miRNAs and their predicated targets have been confirmed by qRT-PCR. These results indicate that these miRNAs, especially miR159, miR166, miR167 and miR5072 could be involved in the extensive regulation of gene expression in response to hybrid necrosis.https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117507&type=printable
spellingShingle Jianping Zhou
Yan Cheng
Meiqi Yin
Ennian Yang
Wenping Gong
Cheng Liu
Xuelian Zheng
Kejun Deng
Zhenglong Ren
Yong Zhang
Identification of novel miRNAs and miRNA expression profiling in wheat hybrid necrosis.
PLoS ONE
title Identification of novel miRNAs and miRNA expression profiling in wheat hybrid necrosis.
title_full Identification of novel miRNAs and miRNA expression profiling in wheat hybrid necrosis.
title_fullStr Identification of novel miRNAs and miRNA expression profiling in wheat hybrid necrosis.
title_full_unstemmed Identification of novel miRNAs and miRNA expression profiling in wheat hybrid necrosis.
title_short Identification of novel miRNAs and miRNA expression profiling in wheat hybrid necrosis.
title_sort identification of novel mirnas and mirna expression profiling in wheat hybrid necrosis
url https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0117507&type=printable
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