Case Report: Perhaps we can do more when paradoxical embolism meets thrombophilia: inspiration from a special case
This study reported a rare case of Paradoxical Embolism complicated with thrombophilia. New thrombosis still existed after active treatment, and the existence of thrombus-prone gene was confirmed by gene detection. This patient recovered after improving the treatment plan. It emphasizes the importan...
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2025-08-01
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| Series: | Frontiers in Cardiovascular Medicine |
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| Online Access: | https://www.frontiersin.org/articles/10.3389/fcvm.2025.1608644/full |
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| author | Xiaomin Xue Muhua Dai Lisha Pang Jiayan Li Chunlian Ji Jianbiao Meng Wei Zhang |
| author_facet | Xiaomin Xue Muhua Dai Lisha Pang Jiayan Li Chunlian Ji Jianbiao Meng Wei Zhang |
| author_sort | Xiaomin Xue |
| collection | DOAJ |
| description | This study reported a rare case of Paradoxical Embolism complicated with thrombophilia. New thrombosis still existed after active treatment, and the existence of thrombus-prone gene was confirmed by gene detection. This patient recovered after improving the treatment plan. It emphasizes the importance of genetic testing to improve the diagnosis and treatment plan. This study comprehensively recorded the whole diagnosis and treatment process, including multidisciplinary collaboration, imaging diagnosis and personalized treatment strategies, which provided valuable guidance for similar clinical cases. |
| format | Article |
| id | doaj-art-661b31f100434cbf99643a3252a0ce67 |
| institution | Kabale University |
| issn | 2297-055X |
| language | English |
| publishDate | 2025-08-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Cardiovascular Medicine |
| spelling | doaj-art-661b31f100434cbf99643a3252a0ce672025-08-20T03:41:49ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2025-08-011210.3389/fcvm.2025.16086441608644Case Report: Perhaps we can do more when paradoxical embolism meets thrombophilia: inspiration from a special caseXiaomin Xue0Muhua Dai1Lisha Pang2Jiayan Li3Chunlian Ji4Jianbiao Meng5Wei Zhang6Institute of Basic Experiments, Zhejiang Academy of Traditional Chinese Medicine, Hangzhou, ChinaDepartment of Critical Care Units, Tongde Hospital of Zhejiang Province, Hangzhou, ChinaDepartment of Critical Care Units, Tongde Hospital of Zhejiang Province, Hangzhou, ChinaDepartment of Critical Care Units, Tongde Hospital of Zhejiang Province, Hangzhou, ChinaDepartment of Critical Care Units, Tongde Hospital of Zhejiang Province, Hangzhou, ChinaDepartment of Critical Care Units, Tongde Hospital of Zhejiang Province, Hangzhou, ChinaDepartment of Cardiology, Tongde Hospital of Zhejiang Province, Hangzhou, ChinaThis study reported a rare case of Paradoxical Embolism complicated with thrombophilia. New thrombosis still existed after active treatment, and the existence of thrombus-prone gene was confirmed by gene detection. This patient recovered after improving the treatment plan. It emphasizes the importance of genetic testing to improve the diagnosis and treatment plan. This study comprehensively recorded the whole diagnosis and treatment process, including multidisciplinary collaboration, imaging diagnosis and personalized treatment strategies, which provided valuable guidance for similar clinical cases.https://www.frontiersin.org/articles/10.3389/fcvm.2025.1608644/fullparadoxical embolismpulmonary embolismacute cerebral infarctionvenous thromboembolismplasminogen activator inhibitor-1 |
| spellingShingle | Xiaomin Xue Muhua Dai Lisha Pang Jiayan Li Chunlian Ji Jianbiao Meng Wei Zhang Case Report: Perhaps we can do more when paradoxical embolism meets thrombophilia: inspiration from a special case Frontiers in Cardiovascular Medicine paradoxical embolism pulmonary embolism acute cerebral infarction venous thromboembolism plasminogen activator inhibitor-1 |
| title | Case Report: Perhaps we can do more when paradoxical embolism meets thrombophilia: inspiration from a special case |
| title_full | Case Report: Perhaps we can do more when paradoxical embolism meets thrombophilia: inspiration from a special case |
| title_fullStr | Case Report: Perhaps we can do more when paradoxical embolism meets thrombophilia: inspiration from a special case |
| title_full_unstemmed | Case Report: Perhaps we can do more when paradoxical embolism meets thrombophilia: inspiration from a special case |
| title_short | Case Report: Perhaps we can do more when paradoxical embolism meets thrombophilia: inspiration from a special case |
| title_sort | case report perhaps we can do more when paradoxical embolism meets thrombophilia inspiration from a special case |
| topic | paradoxical embolism pulmonary embolism acute cerebral infarction venous thromboembolism plasminogen activator inhibitor-1 |
| url | https://www.frontiersin.org/articles/10.3389/fcvm.2025.1608644/full |
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