Antidepressant-associated sexual dysfunction in outpatients
Abstract Background Antidepressant treatment is related to various sexual dysfunctions. This may cause discontinuation of the medication. This study aims to evaluate the level of sexual dysfunction of antidepressant users and the possible factors linked. Methods Demographic variables and sexual dysf...
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BMC
2025-04-01
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| Series: | BMC Psychiatry |
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| Online Access: | https://doi.org/10.1186/s12888-025-06751-1 |
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| author | Yasir Safak Sena Inal Azizoglu Furkan Bahadır Alptekin Tacettin Kuru Mehmet Emrah Karadere Simge Nur Kurt Kaya Simay Yılmaz Nisa Nur Yıldırım Amine Kılıçtutan Helin Ay Hüseyin Sehit Burhan |
| author_facet | Yasir Safak Sena Inal Azizoglu Furkan Bahadır Alptekin Tacettin Kuru Mehmet Emrah Karadere Simge Nur Kurt Kaya Simay Yılmaz Nisa Nur Yıldırım Amine Kılıçtutan Helin Ay Hüseyin Sehit Burhan |
| author_sort | Yasir Safak |
| collection | DOAJ |
| description | Abstract Background Antidepressant treatment is related to various sexual dysfunctions. This may cause discontinuation of the medication. This study aims to evaluate the level of sexual dysfunction of antidepressant users and the possible factors linked. Methods Demographic variables and sexual dysfunction level of 452 people in total (291 males and 161 females) were assessed by demographic data form and Psychotropic-related Sexual Dysfunction Questionnaire (PreSEXDQ). Results Sexual dysfunction was highly prevalent among both females (88.7%) and males (84.5%). Among females, significant differences were observed based on antidepressant type, with those using bupropion experiencing lower levels of sexual dysfunction compared to those on SSRIs, SNRIs, or vortioxetine. In contrast, no significant differences were found for males. Conclusions This highlights the importance of considering gender and medication type when addressing and managing psychotropic-related sexual dysfunction. Furthermore, additional studies are needed to determine whether a causal relationship exists between psychiatric medication-related sexual dysfunction and treatment discontinuation. |
| format | Article |
| id | doaj-art-6617da58cfc44979939231fb5b1621ea |
| institution | OA Journals |
| issn | 1471-244X |
| language | English |
| publishDate | 2025-04-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Psychiatry |
| spelling | doaj-art-6617da58cfc44979939231fb5b1621ea2025-08-20T01:54:19ZengBMCBMC Psychiatry1471-244X2025-04-012511810.1186/s12888-025-06751-1Antidepressant-associated sexual dysfunction in outpatientsYasir Safak0Sena Inal Azizoglu1Furkan Bahadır Alptekin2Tacettin Kuru3Mehmet Emrah Karadere4Simge Nur Kurt Kaya5Simay Yılmaz6Nisa Nur Yıldırım7Amine Kılıçtutan8Helin Ay9Hüseyin Sehit Burhan10Department of Psychiatry, Ankara Etlik City HospitalDepartment of Psychiatry, Basaksehir Cam and Sakura City HospitalDepartment of Psychiatry, Basaksehir Cam and Sakura City HospitalDepartment of Psychiatry, ALKU Alanya Education and Research HospitalDepartment of Psychiatry, Istanbul Medeniyet UniversityDepartment of Psychiatry, 29 Mayıs State HospitalDepartment of Psychiatry, Basaksehir Cam and Sakura City HospitalDepartment of Psychiatry, Basaksehir Cam and Sakura City HospitalDepartment of Psychiatry, Basaksehir Cam and Sakura City HospitalDepartment of Psychiatry, Basaksehir Cam and Sakura City HospitalDepartment of Psychiatry, Basaksehir Cam and Sakura City HospitalAbstract Background Antidepressant treatment is related to various sexual dysfunctions. This may cause discontinuation of the medication. This study aims to evaluate the level of sexual dysfunction of antidepressant users and the possible factors linked. Methods Demographic variables and sexual dysfunction level of 452 people in total (291 males and 161 females) were assessed by demographic data form and Psychotropic-related Sexual Dysfunction Questionnaire (PreSEXDQ). Results Sexual dysfunction was highly prevalent among both females (88.7%) and males (84.5%). Among females, significant differences were observed based on antidepressant type, with those using bupropion experiencing lower levels of sexual dysfunction compared to those on SSRIs, SNRIs, or vortioxetine. In contrast, no significant differences were found for males. Conclusions This highlights the importance of considering gender and medication type when addressing and managing psychotropic-related sexual dysfunction. Furthermore, additional studies are needed to determine whether a causal relationship exists between psychiatric medication-related sexual dysfunction and treatment discontinuation.https://doi.org/10.1186/s12888-025-06751-1AntidepressantsAntipsychotic selective serotonin reuptake inhibitorsDepressionSexual dysfunctions |
| spellingShingle | Yasir Safak Sena Inal Azizoglu Furkan Bahadır Alptekin Tacettin Kuru Mehmet Emrah Karadere Simge Nur Kurt Kaya Simay Yılmaz Nisa Nur Yıldırım Amine Kılıçtutan Helin Ay Hüseyin Sehit Burhan Antidepressant-associated sexual dysfunction in outpatients BMC Psychiatry Antidepressants Antipsychotic selective serotonin reuptake inhibitors Depression Sexual dysfunctions |
| title | Antidepressant-associated sexual dysfunction in outpatients |
| title_full | Antidepressant-associated sexual dysfunction in outpatients |
| title_fullStr | Antidepressant-associated sexual dysfunction in outpatients |
| title_full_unstemmed | Antidepressant-associated sexual dysfunction in outpatients |
| title_short | Antidepressant-associated sexual dysfunction in outpatients |
| title_sort | antidepressant associated sexual dysfunction in outpatients |
| topic | Antidepressants Antipsychotic selective serotonin reuptake inhibitors Depression Sexual dysfunctions |
| url | https://doi.org/10.1186/s12888-025-06751-1 |
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