MicroRNA-21 Contributes to Acute Liver Injury in LPS-Induced Sepsis Mice by Inhibiting PPARα Expression
The severity of sepsis may be associated with excessive inflammation, thus leading to acute liver injury. MicroRNA-21 is highly expressed in the liver of a variety of inflammation-related diseases, and PPARα is also proved to participate in regulating inflammation. In the present study, the LPS-indu...
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| Main Authors: | Xianjin Du, Miao Wu, Dan Tian, Jianlin Zhou, Lu Wang, Liying Zhan |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
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| Series: | PPAR Research |
| Online Access: | http://dx.doi.org/10.1155/2020/6633022 |
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