The Influence of Obesity on Small Bowel Capsule Endoscopy

Objective. Intestinal motility may be different in obese and nonobese patients, but this has not been determined. Here, we sought to evaluate the effect of obesity on small bowel capsule endoscopy (SBCE). Patients and Methods. We retrospectively analyzed the cases of the 340 patients who underwent S...

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Main Authors: Teppei Omori, Yu Sasaki, Miki Koroku, Harutaka Kambayashi, Shun Murasugi, Maria Yonezawa, Shinichi Nakamura, Katsutoshi Tokushige
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Gastroenterology Research and Practice
Online Access:http://dx.doi.org/10.1155/2022/6396651
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author Teppei Omori
Yu Sasaki
Miki Koroku
Harutaka Kambayashi
Shun Murasugi
Maria Yonezawa
Shinichi Nakamura
Katsutoshi Tokushige
author_facet Teppei Omori
Yu Sasaki
Miki Koroku
Harutaka Kambayashi
Shun Murasugi
Maria Yonezawa
Shinichi Nakamura
Katsutoshi Tokushige
author_sort Teppei Omori
collection DOAJ
description Objective. Intestinal motility may be different in obese and nonobese patients, but this has not been determined. Here, we sought to evaluate the effect of obesity on small bowel capsule endoscopy (SBCE). Patients and Methods. We retrospectively analyzed the cases of the 340 patients who underwent SBCE for small intestinal disease (excluding cases of unobservable total small bowel, small bowel stenosis, and bowel resection) at our hospital during the period January 2014 to December 2020 to extract patient background factors and the bowel transit times of SBCE according to the presence/absence of obesity (defined as a body mass index BMI≥25 kg/m2). Results. The obese group was 54 patients (nonobese, n=286). The small bowel transit time (SBTT) was significantly shorter in the obese patients compared to the nonobese patients (p=0.0026), and when we divided the patients by their short/long SBTTs using 216.5 min as the cutoff, we observed significant between-group differences in the patients’ age (≥60 years) and in the patients’ hospitalization status at the time of the SBCE examination. A multivariate analysis revealed that hospitalized status at the examination is a factor contributing significantly to a long SBTT (OR 0.25, 95% CI: 0.15–0.42, p<0.0001). An analysis using the outpatient/inpatient conditions showed that obesity was an independent factor in the inpatient status at the SBCE examination with a significant short SBTT (OR 2.91, 95% CI: 1.06–7.97, p=0.0380). Constipation at the examination was also a factor contributing to a long SBTT (OR 0.26, 95% CI: 0.07–0.99, p=0.0493). Conclusion. The SBTT of the SBCE was significantly shorter in the obese patients. This tendency was especially evident in the hospitalized state.
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spelling doaj-art-660355d7435b47b1a9ed9c8dde64c2e72025-08-20T02:23:48ZengWileyGastroenterology Research and Practice1687-630X2022-01-01202210.1155/2022/6396651The Influence of Obesity on Small Bowel Capsule EndoscopyTeppei Omori0Yu Sasaki1Miki Koroku2Harutaka Kambayashi3Shun Murasugi4Maria Yonezawa5Shinichi Nakamura6Katsutoshi Tokushige7Institute of GastroenterologyInstitute of GastroenterologyInstitute of GastroenterologyInstitute of GastroenterologyInstitute of GastroenterologyInstitute of GastroenterologyInstitute of GastroenterologyInstitute of GastroenterologyObjective. Intestinal motility may be different in obese and nonobese patients, but this has not been determined. Here, we sought to evaluate the effect of obesity on small bowel capsule endoscopy (SBCE). Patients and Methods. We retrospectively analyzed the cases of the 340 patients who underwent SBCE for small intestinal disease (excluding cases of unobservable total small bowel, small bowel stenosis, and bowel resection) at our hospital during the period January 2014 to December 2020 to extract patient background factors and the bowel transit times of SBCE according to the presence/absence of obesity (defined as a body mass index BMI≥25 kg/m2). Results. The obese group was 54 patients (nonobese, n=286). The small bowel transit time (SBTT) was significantly shorter in the obese patients compared to the nonobese patients (p=0.0026), and when we divided the patients by their short/long SBTTs using 216.5 min as the cutoff, we observed significant between-group differences in the patients’ age (≥60 years) and in the patients’ hospitalization status at the time of the SBCE examination. A multivariate analysis revealed that hospitalized status at the examination is a factor contributing significantly to a long SBTT (OR 0.25, 95% CI: 0.15–0.42, p<0.0001). An analysis using the outpatient/inpatient conditions showed that obesity was an independent factor in the inpatient status at the SBCE examination with a significant short SBTT (OR 2.91, 95% CI: 1.06–7.97, p=0.0380). Constipation at the examination was also a factor contributing to a long SBTT (OR 0.26, 95% CI: 0.07–0.99, p=0.0493). Conclusion. The SBTT of the SBCE was significantly shorter in the obese patients. This tendency was especially evident in the hospitalized state.http://dx.doi.org/10.1155/2022/6396651
spellingShingle Teppei Omori
Yu Sasaki
Miki Koroku
Harutaka Kambayashi
Shun Murasugi
Maria Yonezawa
Shinichi Nakamura
Katsutoshi Tokushige
The Influence of Obesity on Small Bowel Capsule Endoscopy
Gastroenterology Research and Practice
title The Influence of Obesity on Small Bowel Capsule Endoscopy
title_full The Influence of Obesity on Small Bowel Capsule Endoscopy
title_fullStr The Influence of Obesity on Small Bowel Capsule Endoscopy
title_full_unstemmed The Influence of Obesity on Small Bowel Capsule Endoscopy
title_short The Influence of Obesity on Small Bowel Capsule Endoscopy
title_sort influence of obesity on small bowel capsule endoscopy
url http://dx.doi.org/10.1155/2022/6396651
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