Harnessing miRNA dynamics in HIV-1-infected macrophages: Unveiling new targeted therapeutics using systems biology

Harnessing miRNA dynamics in HIV-1-infected macrophages: Unveiling new targeted therapeutics using systems biology

Background: The interaction between HIV-1 and host immune cells, particularly macrophages, is crucial in understanding viral persistence and pathogenesis. This study aims to explore the impact of HIV-1 infection on macrophage microRNA (miRNA) expression profiles using a systems biology approach to u...

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Bibliographic Details
Main Authors: R. Harshithkumar, Mollina Kaul, Madhuri Chandane-Tak, Nikhat J. Siddiqi, Abdul Malik, Abdul Arif Khan, Anupam Mukherjee
Format: Article
Language:English
Published: Elsevier 2025-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
HIV-1
MiRNA
Microarray
Gene ontology
Biological networks
Molecular function
Online Access:http://www.sciencedirect.com/science/article/pii/S2001037025001618
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