Multi-analyte liquid biopsy approaches for early detection of esophageal cancer: the expanding role of ctDNA

Multi-analyte liquid biopsy approaches for early detection of esophageal cancer: the expanding role of ctDNA

Circulating tumor DNA (ctDNA) has emerged as a promising biomarker for the early detection of esophageal cancer (EC), offering a minimally invasive means to assess tumor-derived genomic and epigenomic alterations. This review synthesizes current data on ctDNA biology, detection technologies, diagnos...

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Bibliographic Details
Main Authors: Derek Tai, Kareem Latif, Pranati Shah, Daniel Park, Christiana Crook, Sofia Guzman, Gagandeep Brar, Daneng Li, Dani Castillo
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-08-01
Series:Frontiers in Oncology
Subjects:
CtDNA
esophageal cancer
early detection
liquid biopsy
biomarker
esophageal adenocarcinoma
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2025.1622984/full
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