Carbon nanodots-based C-dips for rapid colorimetric detection of clinically important metal ions
Owing to unique physical and optical properties, fluorescent carbon dots (C-dots) are used in various biomedical applications. In this study, C-dots have been integrated as sensing agent on paper surface for colorimetric determination of clinically important analytes. Polyacrylamide-based C-dots co...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-06-01
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| Series: | Kuwait Journal of Science |
| Online Access: | https://journalskuwait.org/kjs/index.php/KJS/article/view/13997 |
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| Summary: | Owing to unique physical and optical properties, fluorescent carbon dots (C-dots) are used in various biomedical applications. In this study, C-dots have been integrated as sensing agent on paper surface for colorimetric determination of clinically important analytes. Polyacrylamide-based C-dots coated C-dips showed visible color change from white to brown for iron (Fe2+, Fe3+) sample. Moreover, iron and copper (Cu2+) samples showed significant quenching of C-dots under UV. Images captured with/without UV were analyzed to study the relationship between different iron and copper concentrations and colorimetric intensity values. Color intensity and fluorescence showed a linear relationship with concentrations of iron and copper (Range: 1×10-4 to 1×10-2 M, Linearity: R2 = 0.94). LOD from the paper sensor showed a sensitivity of 3.89×10-5 μM, 4.65×10-5 μM and 6.7×10-5 μM for Fe3+, Fe2+ and Cu2+ respectively, reflecting its reliability as low-cost sensing solution to analyze clinically relevant analytes as reported in current study.
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| ISSN: | 2307-4108 2307-4116 |