The Association of Toll-like Receptor-9 Gene Single-Nucleotide Polymorphism and <i>AK155(IL-26)</i> Serum Levels with Chronic Obstructive Pulmonary Disease Exacerbation Risk: A Case-Controlled Study with Bioinformatics Analysis

The Association of Toll-like Receptor-9 Gene Single-Nucleotide Polymorphism and <i>AK155(IL-26)</i> Serum Levels with Chronic Obstructive Pulmonary Disease Exacerbation Risk: A Case-Controlled Study with Bioinformatics Analysis

<b>Background:</b> A crucial challenge is the determination of chronic obstructive pulmonary disease (COPD) immune-related mechanisms, where one of the important components of the inflammatory axes in COPD is Toll-like receptor-9 (TLR9) and interleukin-26 AK155(IL-26). Aim: To examine th...

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Main Authors: Entsar R. Mokhtar, Salwa I. Elshennawy, Heba Elhakeem, Rayyh A. M. Saleh, Sawsan Bakr Elsawy, Khadiga S. M. Salama, Maha Fathy Mohamed, Rania Hamid Bahi, Hayam H. Mansour, Sammar Ahmed Kasim Mahmoud, Marwa M. Hassan, Sara M. Elhadad, Hanaa Mohammed Eid El Sayed, Aliaa N. Mohamed, Nadia M. Hamdy
Format: Article
Language:English
Published: MDPI AG 2025-03-01
Series:Biomedicines
Subjects:
chronic obstructive pulmonary disease (COPD)
single-nucleotide polymorphism (SNP)
toll-like receptor-9 (TLR9)
interleukin-26 AK155(IL-26)
exacerbation
forced expiratory volume
Online Access:https://www.mdpi.com/2227-9059/13/3/613
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