Rates of gyrase supercoiling and transcription elongation control supercoil density in a bacterial chromosome.
Gyrase catalyzes negative supercoiling of DNA in an ATP-dependent reaction that helps condense bacterial chromosomes into a compact interwound "nucleoid." The supercoil density (σ) of prokaryotic DNA occurs in two forms. Diffusible supercoil density (σ(D)) moves freely around the chromosom...
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| Main Authors: | Nikolay Rovinskiy, Andrews Akwasi Agbleke, Olga Chesnokova, Zhenhua Pang, N Patrick Higgins |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2012-01-01
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| Series: | PLoS Genetics |
| Online Access: | https://journals.plos.org/plosgenetics/article/file?id=10.1371/journal.pgen.1002845&type=printable |
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