An eight-year retrospective analysis of antenatal screening results for syphilis: is it still cost effective?
Introduction: This study aimed to document the prevalence of syphilis among pregnant women in Turkey. Methodology: In this retrospective cohort study, a total of 63,276 sera obtained between January 2007 and June 2014 from women who were routinely screened for syphilis as a part of antenatal care a...
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| Format: | Article |
| Language: | English |
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The Journal of Infection in Developing Countries
2015-09-01
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| Series: | Journal of Infection in Developing Countries |
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| Online Access: | https://jidc.org/index.php/journal/article/view/6064 |
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| author | Tugba Ensari Ayse Kirbas Ayse Seval Ozgu-Erdinc Sibel Gokay Saygan Salim Erkaya Dilek Uygur Nuri Danisman |
| author_facet | Tugba Ensari Ayse Kirbas Ayse Seval Ozgu-Erdinc Sibel Gokay Saygan Salim Erkaya Dilek Uygur Nuri Danisman |
| author_sort | Tugba Ensari |
| collection | DOAJ |
| description | Introduction: This study aimed to document the prevalence of syphilis among pregnant women in Turkey.
Methodology: In this retrospective cohort study, a total of 63,276 sera obtained between January 2007 and June 2014 from women who were routinely screened for syphilis as a part of antenatal care at a tertiary referral hospital in Turkey were analyzed. Serological screening was done with the rapid plasma reagin (RPR) test on venous blood samples. Treponema pallidum hemagglutination assay (TPHA) was the confirmation test for the diagnosis of syphilis in patients who had positive results in the screening test.
Results: Between 2007 and the first six months of 2014, 41 RPR+ and only five confirmed syphilis-positive patients were determined. The syphilis seroprevalence rate was 0.0648%. Within these years, there was no case of congenital syphilis detected in the hospital.
Conclusion: As there is evidence of effective screening of syphilis contributing to the effective treatment and prevention of adverse outcomes, routine antenatal screening of syphilis is recommended. The rationale depends on the consideration of the serious results of not treating the disease and the cost effectiveness of screening.
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| format | Article |
| id | doaj-art-65eb8a4670e94ebda00939baef740146 |
| institution | Kabale University |
| issn | 1972-2680 |
| language | English |
| publishDate | 2015-09-01 |
| publisher | The Journal of Infection in Developing Countries |
| record_format | Article |
| series | Journal of Infection in Developing Countries |
| spelling | doaj-art-65eb8a4670e94ebda00939baef7401462025-08-20T03:48:47ZengThe Journal of Infection in Developing CountriesJournal of Infection in Developing Countries1972-26802015-09-0190910.3855/jidc.6064An eight-year retrospective analysis of antenatal screening results for syphilis: is it still cost effective?Tugba Ensari0Ayse Kirbas1Ayse Seval Ozgu-Erdinc2Sibel Gokay Saygan3Salim Erkaya4Dilek Uygur5Nuri Danisman6Zekai Tahir Burak Women Health Care, Training and Research Hospital, Ankara, TurkeyZekai Tahir Burak Women Health Care, Training and Research Hospital, Ankara, TurkeyZekai Tahir Burak Women Health Care, Training and Research Hospital, Ankara, TurkeyZekai Tahir Burak Women Health Care, Training and Research Hospital, Ankara, TurkeyZekai Tahir Burak Women Health Care, Training and Research Hospital, Ankara, TurkeyZekai Tahir Burak Women Health Care, Training and Research Hospital, Ankara, TurkeyZekai Tahir Burak Women Health Care, Training and Research Hospital, Ankara, TurkeyIntroduction: This study aimed to document the prevalence of syphilis among pregnant women in Turkey. Methodology: In this retrospective cohort study, a total of 63,276 sera obtained between January 2007 and June 2014 from women who were routinely screened for syphilis as a part of antenatal care at a tertiary referral hospital in Turkey were analyzed. Serological screening was done with the rapid plasma reagin (RPR) test on venous blood samples. Treponema pallidum hemagglutination assay (TPHA) was the confirmation test for the diagnosis of syphilis in patients who had positive results in the screening test. Results: Between 2007 and the first six months of 2014, 41 RPR+ and only five confirmed syphilis-positive patients were determined. The syphilis seroprevalence rate was 0.0648%. Within these years, there was no case of congenital syphilis detected in the hospital. Conclusion: As there is evidence of effective screening of syphilis contributing to the effective treatment and prevention of adverse outcomes, routine antenatal screening of syphilis is recommended. The rationale depends on the consideration of the serious results of not treating the disease and the cost effectiveness of screening. https://jidc.org/index.php/journal/article/view/6064syphilisprevalencepregnancyantenatal care |
| spellingShingle | Tugba Ensari Ayse Kirbas Ayse Seval Ozgu-Erdinc Sibel Gokay Saygan Salim Erkaya Dilek Uygur Nuri Danisman An eight-year retrospective analysis of antenatal screening results for syphilis: is it still cost effective? Journal of Infection in Developing Countries syphilis prevalence pregnancy antenatal care |
| title | An eight-year retrospective analysis of antenatal screening results for syphilis: is it still cost effective? |
| title_full | An eight-year retrospective analysis of antenatal screening results for syphilis: is it still cost effective? |
| title_fullStr | An eight-year retrospective analysis of antenatal screening results for syphilis: is it still cost effective? |
| title_full_unstemmed | An eight-year retrospective analysis of antenatal screening results for syphilis: is it still cost effective? |
| title_short | An eight-year retrospective analysis of antenatal screening results for syphilis: is it still cost effective? |
| title_sort | eight year retrospective analysis of antenatal screening results for syphilis is it still cost effective |
| topic | syphilis prevalence pregnancy antenatal care |
| url | https://jidc.org/index.php/journal/article/view/6064 |
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