Green Synthesis of Nanocomposite: Based on [Eugenol and Metal Oxides], Characterization and Biomedical Applications

Eugenol (EUG) was reacted as a matrix with a mixture of metal oxides (ZnO and CuO) have been prepared from metal acetate, Zn (CH3CO2)2 and Cu (CH3CO2)2 as precursors and using ethylene glycol (EG) as a solvent for synthesis the [Eug/ ZnO: CuO] nanocomposite using Sol-Gel method. The synthesized nan...

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Main Authors: Fatin A. Abd AL-Qadir, Basim I. Al-Abdaly
Format: Article
Language:English
Published: University of Baghdad, College of Science for Women 2024-09-01
Series:مجلة بغداد للعلوم
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Online Access:https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/8324
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author Fatin A. Abd AL-Qadir
Basim I. Al-Abdaly
author_facet Fatin A. Abd AL-Qadir
Basim I. Al-Abdaly
author_sort Fatin A. Abd AL-Qadir
collection DOAJ
description Eugenol (EUG) was reacted as a matrix with a mixture of metal oxides (ZnO and CuO) have been prepared from metal acetate, Zn (CH3CO2)2 and Cu (CH3CO2)2 as precursors and using ethylene glycol (EG) as a solvent for synthesis the [Eug/ ZnO: CuO] nanocomposite using Sol-Gel method. The synthesized nanocomposite was characterized using techniques (FT-IR, AFM, SEM, EDX, and XRD), where the average particle diameter was found to be within the nanoscale range. It was also observed that the prepared nanomaterial was in the form of rods with good homogeneity distribution. In order to stand on the obtained nanoscale properties, those properties were employed in terms of nanoscale dimension and shape characteristics, to investigate the effectiveness of the prepared nanocomposite [Eug/ ZnO: CuO] as antimicrobials (antibacterial and antifungal) activity against two types of bacteria [Escherichia Coli (-) (E. coli), and Staphylococcus aureus (+) (S. aureus)], and one type of fungi [Candida albicaus (C. albicaus)], where it showed acceptable results. The effectiveness of the prepared nanocomposite was also measured as the antioxidant against free radicals and it showed a good scavenging ratio. In addition, the cytotoxic effect of [Eug/ ZnO: CuO] nanocomposite on breast cancer cells (MCF-7) was studied, and it showed acceptable results in killing the cell line (MCF-7) at high concentrations.    
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series مجلة بغداد للعلوم
spelling doaj-art-65eb06027ac547678f0d36a5901d9e222025-08-20T03:14:42ZengUniversity of Baghdad, College of Science for Womenمجلة بغداد للعلوم2078-86652411-79862024-09-0121910.21123/bsj.2024.8324Green Synthesis of Nanocomposite: Based on [Eugenol and Metal Oxides], Characterization and Biomedical ApplicationsFatin A. Abd AL-Qadir0https://orcid.org/0000-0003-2154-3402Basim I. Al-Abdaly1Department of chemistry, College of Science, University of Baghdad, Baghdad, Iraq.Department of chemistry, College of Science, University of Baghdad, Baghdad, Iraq. Eugenol (EUG) was reacted as a matrix with a mixture of metal oxides (ZnO and CuO) have been prepared from metal acetate, Zn (CH3CO2)2 and Cu (CH3CO2)2 as precursors and using ethylene glycol (EG) as a solvent for synthesis the [Eug/ ZnO: CuO] nanocomposite using Sol-Gel method. The synthesized nanocomposite was characterized using techniques (FT-IR, AFM, SEM, EDX, and XRD), where the average particle diameter was found to be within the nanoscale range. It was also observed that the prepared nanomaterial was in the form of rods with good homogeneity distribution. In order to stand on the obtained nanoscale properties, those properties were employed in terms of nanoscale dimension and shape characteristics, to investigate the effectiveness of the prepared nanocomposite [Eug/ ZnO: CuO] as antimicrobials (antibacterial and antifungal) activity against two types of bacteria [Escherichia Coli (-) (E. coli), and Staphylococcus aureus (+) (S. aureus)], and one type of fungi [Candida albicaus (C. albicaus)], where it showed acceptable results. The effectiveness of the prepared nanocomposite was also measured as the antioxidant against free radicals and it showed a good scavenging ratio. In addition, the cytotoxic effect of [Eug/ ZnO: CuO] nanocomposite on breast cancer cells (MCF-7) was studied, and it showed acceptable results in killing the cell line (MCF-7) at high concentrations.     https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/8324Biomedical, Eugenol, Green synthesis, Metal oxides, Nanocomposite
spellingShingle Fatin A. Abd AL-Qadir
Basim I. Al-Abdaly
Green Synthesis of Nanocomposite: Based on [Eugenol and Metal Oxides], Characterization and Biomedical Applications
مجلة بغداد للعلوم
Biomedical, Eugenol, Green synthesis, Metal oxides, Nanocomposite
title Green Synthesis of Nanocomposite: Based on [Eugenol and Metal Oxides], Characterization and Biomedical Applications
title_full Green Synthesis of Nanocomposite: Based on [Eugenol and Metal Oxides], Characterization and Biomedical Applications
title_fullStr Green Synthesis of Nanocomposite: Based on [Eugenol and Metal Oxides], Characterization and Biomedical Applications
title_full_unstemmed Green Synthesis of Nanocomposite: Based on [Eugenol and Metal Oxides], Characterization and Biomedical Applications
title_short Green Synthesis of Nanocomposite: Based on [Eugenol and Metal Oxides], Characterization and Biomedical Applications
title_sort green synthesis of nanocomposite based on eugenol and metal oxides characterization and biomedical applications
topic Biomedical, Eugenol, Green synthesis, Metal oxides, Nanocomposite
url https://bsj.uobaghdad.edu.iq/index.php/BSJ/article/view/8324
work_keys_str_mv AT fatinaabdalqadir greensynthesisofnanocompositebasedoneugenolandmetaloxidescharacterizationandbiomedicalapplications
AT basimialabdaly greensynthesisofnanocompositebasedoneugenolandmetaloxidescharacterizationandbiomedicalapplications