LEFT VENTRICLE DIASTOLIC DYSFUNCTION IN PATIENTS WITH ANTERIOR WALL MYOCARDIAL INFARCTION AND DRUG PREVENTION OF CONGESTIVE HEART FAILURE (A LONG-TERM OBSERVATION)
The aim of this study was to evaluate LV diastolic reserve (DR) and possibilities of long>term prevention of congestive heart failure with long>term administration of Captopril and Carvedilol in patients with anterior wall MI and silent LV diastolic dysfunction. DR was measured in pati...
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| Main Authors: | , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
«FIRMA «SILICEA» LLC
2003-08-01
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| Series: | Российский кардиологический журнал |
| Subjects: | |
| Online Access: | https://russjcardiol.elpub.ru/jour/article/view/1770 |
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| Summary: | The aim of this study was to evaluate LV diastolic reserve (DR) and possibilities of long>term prevention of congestive heart failure with long>term administration of Captopril and Carvedilol in patients with anterior wall MI and silent LV diastolic dysfunction. DR was measured in patients with MI by means of volume stress, and accordingly the patients were divided into 2 groups: 1st (n=20) with preserved LV DR treated by Streptokinase, aspirin, heparin, captopril and atenolol, 2nd (n=43) with decreased LV DR. Patients with decreased LV DR were divided into groups: A – treatment identical to the 1st group, B – atenolol substituted for carvediolol. The results of the study have shown that severe types of LV DD – congestive HF – developed only in patients with decreased LV DR, whereas long>term (6 months) combined administration of Captopril and Carvedilol reliably decreases the incidence of congestive HF in patients with MI. |
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| ISSN: | 1560-4071 2618-7620 |