Prospectives of T-cells genetic programming in adoptive immunotherapy of malignancies

The article reviews the literature on adoptive T-cell therapy of malignancies. Adoptive T-cell transfer allows treatment of metastatic disease on the late stages of certain tumors. The method has a number of advantages before traditional antitumor therapy. The special attention is paid to the possib...

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Bibliographic Details
Main Authors: O. L. Morozova, V. V. Yakovlev, N. A. Sushentsev
Format: Article
Language:Russian
Published: Federal State Autonomous Educational Institution of Higher Education I.M. Sechenov First Moscow State Medical University of the Ministry of Health of the Russian Federation (Sechenov University) 2016-09-01
Series:Сеченовский вестник
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Online Access:https://www.sechenovmedj.com/jour/article/view/640
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Summary:The article reviews the literature on adoptive T-cell therapy of malignancies. Adoptive T-cell transfer allows treatment of metastatic disease on the late stages of certain tumors. The method has a number of advantages before traditional antitumor therapy. The special attention is paid to the possibility of adoptive cells genetic programming, which increases the treatment effectiveness and safety in cancer patients. The article also discusses the method introduction into clinical practice.
ISSN:2218-7332
2658-3348