Drug Interactions and Risk of Bleeding among Patients with Atrial Fibrillation (AF) Discharged with Warfarin

The objective of this study was to examine and evaluate the frequency of bleeding and serious drug interactions among patients with atrial fibrillation (AF) treated with oral anticoagulant [Warfarin]. A random sample of 59 patients from Al-Watni government hospital in Nablus with a principal or seco...

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Main Authors: Nidal Jaradat, Moueen Elawee, Asaad Al-Shakh
Format: Article
Language:English
Published: An-Najah National University 2006-09-01
Series:مجلة جامعة النجاح للأبحاث العلوم الطبيعية
Online Access:https://journals.najah.edu/media/journals/full_texts/drug-interactions-and-risk-bleeding-among-patients-atrial-fibrillation-af-discharged-warfarin.pdf
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author Nidal Jaradat
Moueen Elawee
Asaad Al-Shakh
author_facet Nidal Jaradat
Moueen Elawee
Asaad Al-Shakh
author_sort Nidal Jaradat
collection DOAJ
description The objective of this study was to examine and evaluate the frequency of bleeding and serious drug interactions among patients with atrial fibrillation (AF) treated with oral anticoagulant [Warfarin]. A random sample of 59 patients from Al-Watni government hospital in Nablus with a principal or secondary discharge diagnosis of AF was identified. All drug and clinical data were abstracted from the patient's files. We excluded patients who were less than 65 years of age, or left the hospital against medical advice, and those whose AF was transient or could not be confirmed. Of the original 59 AF patients, 19 were cliagnosed who were discharged on Warfarin. The mean age for these patients was 71.7 years. Among the patients discharged on Warfarin, 94.7 % had one or more drug – drug interactions that could lead to increased risk of bleeding. Many patients discharged on Warfarin were having multiple interacting drugs. Patient counseling and follow-up monitoring are essential and should be carried out to minimize the risk of bleeding and other complications.
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publisher An-Najah National University
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series مجلة جامعة النجاح للأبحاث العلوم الطبيعية
spelling doaj-art-65d66a4bf0d64d149b09daa08ca3cf232025-08-20T03:44:03ZengAn-Najah National Universityمجلة جامعة النجاح للأبحاث العلوم الطبيعية1727-21142311-88652006-09-0120112713410.35552/anujr.a.20.1.598Drug Interactions and Risk of Bleeding among Patients with Atrial Fibrillation (AF) Discharged with WarfarinNidal Jaradat0Moueen Elawee1Asaad Al-Shakh2Faculty of Medicine and Health Sciences, An-Najah National University, Nablus, PalestineNoneNoneThe objective of this study was to examine and evaluate the frequency of bleeding and serious drug interactions among patients with atrial fibrillation (AF) treated with oral anticoagulant [Warfarin]. A random sample of 59 patients from Al-Watni government hospital in Nablus with a principal or secondary discharge diagnosis of AF was identified. All drug and clinical data were abstracted from the patient's files. We excluded patients who were less than 65 years of age, or left the hospital against medical advice, and those whose AF was transient or could not be confirmed. Of the original 59 AF patients, 19 were cliagnosed who were discharged on Warfarin. The mean age for these patients was 71.7 years. Among the patients discharged on Warfarin, 94.7 % had one or more drug – drug interactions that could lead to increased risk of bleeding. Many patients discharged on Warfarin were having multiple interacting drugs. Patient counseling and follow-up monitoring are essential and should be carried out to minimize the risk of bleeding and other complications.https://journals.najah.edu/media/journals/full_texts/drug-interactions-and-risk-bleeding-among-patients-atrial-fibrillation-af-discharged-warfarin.pdf
spellingShingle Nidal Jaradat
Moueen Elawee
Asaad Al-Shakh
Drug Interactions and Risk of Bleeding among Patients with Atrial Fibrillation (AF) Discharged with Warfarin
مجلة جامعة النجاح للأبحاث العلوم الطبيعية
title Drug Interactions and Risk of Bleeding among Patients with Atrial Fibrillation (AF) Discharged with Warfarin
title_full Drug Interactions and Risk of Bleeding among Patients with Atrial Fibrillation (AF) Discharged with Warfarin
title_fullStr Drug Interactions and Risk of Bleeding among Patients with Atrial Fibrillation (AF) Discharged with Warfarin
title_full_unstemmed Drug Interactions and Risk of Bleeding among Patients with Atrial Fibrillation (AF) Discharged with Warfarin
title_short Drug Interactions and Risk of Bleeding among Patients with Atrial Fibrillation (AF) Discharged with Warfarin
title_sort drug interactions and risk of bleeding among patients with atrial fibrillation af discharged with warfarin
url https://journals.najah.edu/media/journals/full_texts/drug-interactions-and-risk-bleeding-among-patients-atrial-fibrillation-af-discharged-warfarin.pdf
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AT moueenelawee druginteractionsandriskofbleedingamongpatientswithatrialfibrillationafdischargedwithwarfarin
AT asaadalshakh druginteractionsandriskofbleedingamongpatientswithatrialfibrillationafdischargedwithwarfarin