Human IFN-κ Inhibited Respiratory RNA Virus Replication Dependent on Cell-to-Cell Interaction in the Early Phase

Human IFN-κ Inhibited Respiratory RNA Virus Replication Dependent on Cell-to-Cell Interaction in the Early Phase

Abstract. Background:. Interferon kappa (IFN-κ) is a type I interferon (IFN-I) that inhibits virus replication by evoking interferon-stimulated genes (ISGs). However, as an evolutionarily ancient interferon, IFN-κ may function differently from the later emerged interferon-α and β. Methods:. Conventi...

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Main Authors: Weihui Fu, Peng Sun, Jun Fan, Longfei Ding, Songhua Yuan, Guanxing Zhai, Miaomiao Zhang, Chenli Qiu, Shuye Zhang, Xiaoyan Zhang, Jianqing Xu, Haijuan Wang
Format: Article
Language:English
Published: Wolters Kluwer Health - Lippincott Williams Wilkins 2022-04-01
Series:​​​​​​​​Infectious Diseases & Immunity
Online Access:http://journals.lww.com/10.1097/ID9.0000000000000049
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